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ATP11 Atp11p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855401, updated on 18-Sep-2024

Summary

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Official Symbol
ATP11
Official Full Name
Atp11p
Primary source
SGD:S000005259
Locus tag
YNL315C
See related
AllianceGenome:SGD:S000005259; FungiDB:YNL315C; VEuPathDB:YNL315C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables unfolded protein binding activity. Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrion. Orthologous to human ATPAF1 (ATP synthase mitochondrial F1 complex assembly factor 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ATP11 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (43324..44280, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene cleavage polyadenylation factor subunit PFS2 Neighboring gene prephenate dehydratase PHA2 Neighboring gene Dal82p Neighboring gene tetratricopeptide repeat-containing protein EMW1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A purified subfragment of yeast Atp11p retains full molecular chaperone activity. Hinton A, et al. J Biol Chem, 2003 Sep 5. PMID 12829692
  2. An accessible hydrophobic surface is a key element of the molecular chaperone action of Atp11p. Sheluho D, et al. J Biol Chem, 2001 Oct 26. PMID 11522798
  3. Identification of functional domains in Atp11p. Protein required for assembly of the mitochondrial F1-ATPase in yeast. Wang ZG, et al. J Biol Chem, 1996 Mar 1. PMID 8617760
  4. Bacterial production and characterization of ATP11, a yeast protein required for mitochondrial F1-ATPase assembly. White M, et al. Arch Biochem Biophys, 1995 May 10. PMID 7771799
  5. The assembly factor Atp11p binds to the beta-subunit of the mitochondrial F(1)-ATPase. Wang ZG, et al. J Biol Chem, 2000 Feb 25. PMID 10681564

See all (66) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial proton-transporting ATP synthase complex assembly IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein-containing complex assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Atp11p
NP_014084.1
  • Molecular chaperone; required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; N-terminally propionylated in vivo

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    43324..44280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183153.1 → NP_014084.1  TPA: Atp11p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014084.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0N0, P32453
    UniProtKB/TrEMBL
    A6ZSG5, B3LPE9, C7GWR2, C8ZGL0, G2WLF4, N1NWG8
    Conserved Domains (1) summary
    pfam06644
    Location:40 → 310
    ATP11; ATP11 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32453.1

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