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PEX17 Pex17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855507, updated on 2-Nov-2024

Summary

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Official Symbol
PEX17
Official Full Name
Pex17p
Primary source
SGD:S000005158
Locus tag
YNL214W
See related
AllianceGenome:SGD:S000005158; FungiDB:YNL214W; VEuPathDB:YNL214W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PAS9
Summary
Involved in protein import into peroxisome matrix, docking. Located in peroxisomal membrane. Part of peroxisomal importomer complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PEX17 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (245617..246216)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene DNA-binding transcription factor RAP1 Neighboring gene Ies2p Neighboring gene Rrg9p Neighboring gene Vid27p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Towards the molecular architecture of the peroxisomal receptor docking complex. Lill P, et al. Proc Natl Acad Sci U S A, 2020 Dec 29. PMID 33323485, Free PMC Article
  2. Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery. Huhse B, et al. J Cell Biol, 1998 Jan 12. PMID 9425153, Free PMC Article
  3. Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery. Girzalsky W, et al. J Biol Chem, 2006 Jul 14. PMID 16679311
  4. Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways. Albertini M, et al. Cell, 1997 Apr 4. PMID 9094717
  5. Distinct Pores for Peroxisomal Import of PTS1 and PTS2 Proteins. Montilla-Martinez M, et al. Cell Rep, 2015 Dec 15. PMID 26673321

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Both, Pex14p and Pex17p interact directly with Dyn2p, but in vivo, Pex17p turned out to be prerequisite for an association of Dyn2p with Pex14p.
    Title: Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery.
  2. Pex19p has a role in targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery
    Title: Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein import into peroxisome matrix, docking IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of peroxisomal importomer complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisomal membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pex17p
NP_014185.1
  • Membrane peroxin of the peroxisomal importomer complex; complex facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    245617..246216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183052.1 → NP_014185.1  TPA: Pex17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014185.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0X6, P40155
    UniProtKB/TrEMBL
    A6ZRM6, B3LP58, B5VQJ8, C7GPE3, G2WLP9, N1NX91
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40155.1

Gene LinkOut

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