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NOP13 Nop13p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855547, updated on 18-Sep-2024

Summary

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Official Symbol
NOP13
Official Full Name
Nop13p
Primary source
SGD:S000005119
Locus tag
YNL175C
See related
AllianceGenome:SGD:S000005119; FungiDB:YNL175C; VEuPathDB:YNL175C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA strand annealing activity; RNA strand-exchange activity; and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in nucleolus. Part of preribosome. Orthologous to human RBM23 (RNA binding motif protein 23). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See NOP13 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (307401..308612, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL22 Neighboring gene Tda7p Neighboring gene Mdg1p Neighboring gene anaphase promoting complex subunit 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae. Wu K, et al. Nucleic Acids Res, 2001 Jul 15. PMID 11452019, Free PMC Article
  2. The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome. McCann KL, et al. Elife, 2016 Apr 14. PMID 27077951, Free PMC Article
  3. Puf6 primes 60S pre-ribosome nuclear export at low temperature. Gerhardy S, et al. Nat Commun, 2021 Aug 4. PMID 34349113, Free PMC Article
  4. Yvh1 is required for a late maturation step in the 60S biogenesis pathway. Kemmler S, et al. J Cell Biol, 2009 Sep 21. PMID 19797079, Free PMC Article
  5. Biochemical and genetic characterization of Yra1p in budding yeast. Kashyap AK, et al. Yeast, 2005 Jan 15. PMID 15584090

See all (61) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Nop13p
NP_014224.2
  • Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM); relative distribution to the nucleolus increases upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    307401..308612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183013.2 → NP_014224.2  TPA: Nop13p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014224.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W110, P53883
    UniProtKB/TrEMBL
    A6ZRR0, B3LP26, C7GTE9, C8ZG53, G2WLT3, N1P475
    Conserved Domains (2) summary
    cd12396
    Location:127 → 217
    RRM1_Nop13p_fungi; RNA recognition motif 1 (RRM1) found in yeast nucleolar protein 13 (Nop13p) and similar proteins
    cd12397
    Location:241 → 316
    RRM2_Nop13p_fungi; RNA recognition motif 2 (RRM2) found in yeast nucleolar protein 13 (Nop13p) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53883.2

Gene LinkOut

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