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IBD2 Ibd2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855557, updated on 18-Sep-2024

Summary

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Official Symbol
IBD2
Official Full Name
Ibd2p
Primary source
SGD:S000005108
Locus tag
YNL164C
See related
AllianceGenome:SGD:S000005108; FungiDB:YNL164C; VEuPathDB:YNL164C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitotic spindle assembly checkpoint signaling. Predicted to be located in cytoplasm and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See IBD2 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (325265..326320, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Bni5p Neighboring gene uncharacterized protein Neighboring gene GTPase RIA1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption and basic phenotypic analysis of six novel genes from the left arm of chromosome XIV of Saccharomyces cerevisiae. Dueñas E, et al. Yeast, 1999 Jan 15. PMID 10028186
  2. IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Hwang HS, et al. Genetics, 2002 Jun. PMID 12072457, Free PMC Article
  3. Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. Haarer B, et al. Genes Dev, 2007 Jan 15. PMID 17167106, Free PMC Article
  4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
  5. Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. Addinall SG, et al. PLoS Genet, 2011 Apr. PMID 21490951, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic spindle assembly checkpoint signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitotic spindle assembly checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus NAS
Non-traceable Author Statement
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ibd2p
NP_014235.1
  • Component of the BUB2-dependent spindle checkpoint pathway; interacts with Bfa1p and functions upstream of Bub2p and Bfa1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    325265..326320 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183002.1 → NP_014235.1  TPA: Ibd2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014235.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZRR9, D6W118, P53892
    UniProtKB/TrEMBL
    B3LP20, C7GTE1, C8ZG64, G2WLU2, N1P485
    Conserved Domains (1) summary
    COG5271
    Location:71 → 220
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53892.1

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