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OCA1 putative tyrosine protein phosphatase OCA1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855624, updated on 18-Sep-2024

Summary

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Official Symbol
OCA1
Official Full Name
putative tyrosine protein phosphatase OCA1
Primary source
SGD:S000005043
Locus tag
YNL099C
See related
AllianceGenome:SGD:S000005043; FungiDB:YNL099C; VEuPathDB:YNL099C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable phosphatase activity. Involved in cellular response to oxidative stress. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See OCA1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (438567..439283, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Avt4p Neighboring gene Mic27p Neighboring gene Ras family GTPase RAS2 Neighboring gene Pls1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide. Alic N, et al. Mol Biol Cell, 2001 Jun. PMID 11408586, Free PMC Article
  2. Lipid hydroperoxides activate the mitogen-activated protein kinase Mpk1p in Saccharomyces cerevisiae. Alic N, et al. J Biol Chem, 2003 Oct 24. PMID 12912987
  3. Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Wishart MJ, et al. Trends Biochem Sci, 1998 Aug. PMID 9757831
  4. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Wang H, et al. Mol Cell Proteomics, 2009 Jun. PMID 19176519, Free PMC Article
  5. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Romá-Mateo C, et al. Mol Genet Genomics, 2011 Apr. PMID 21409566

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative tyrosine protein phosphatase OCA1
NP_014300.3
  • Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    438567..439283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182937.3 → NP_014300.3  TPA: putative tyrosine protein phosphatase OCA1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014300.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZRY1, D6W180, P50946, Q45U02
    UniProtKB/TrEMBL
    B3LNV8, B5VQU3, C7GR79, C8ZGD0, G2WM05, N1NZE8
    Conserved Domains (1) summary
    cd14531
    Location:66 → 218
    PFA-DSP_Oca1; atypical dual specificity phosphatases similar to oxidant-induced cell-cycle arrest protein 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50946.1

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