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YIP3 Yip3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855683, updated on 2-Nov-2024

Summary

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Official Symbol
YIP3
Official Full Name
Yip3p
Primary source
SGD:S000004989
Locus tag
YNL044W
See related
AllianceGenome:SGD:S000004989; FungiDB:YNL044W; VEuPathDB:YNL044W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and peroxisome. Orthologous to human RABAC1 (Rab acceptor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See YIP3 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
2
Sequence:
Chromosome: XIV; NC_001146.8 (545268..545877)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene bifunctional aminopeptidase/epoxide hydrolase Neighboring gene tRNA-Pro Neighboring gene uncharacterized protein Neighboring gene Bop3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p. Geng J, et al. Eukaryot Cell, 2005 Jul. PMID 16002643, Free PMC Article
  2. Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins. Calero M, et al. Biochem Biophys Res Commun, 2002 Jan 18. PMID 11785952
  3. Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. Otte S, et al. J Cell Biol, 2001 Feb 5. PMID 11157978, Free PMC Article
  4. Translation- and SRP-independent mRNA targeting to the endoplasmic reticulum in the yeast Saccharomyces cerevisiae. Kraut-Cohen J, et al. Mol Biol Cell, 2013 Oct. PMID 23904265, Free PMC Article
  5. Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis. David Y, et al. Cells, 2022 Apr 22. PMID 35563734, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Yip3 protein may have multiple functions and that its interaction with Rabs is not critical for their recruitment to organelle membranes.
    Title: Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in COPII-coated ER to Golgi transport vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Yip3p
NP_014354.2
  • Protein localized to COPII vesicles; proposed to be involved in ER-to-Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p; integral membrane protein that localizes to the ER, the Golgi apparatus, transport vesicles and the peroxisome; two isoforms exist, a full-length Yip3L (Yip3 Long) and a shorter peroxisomal matrix isoform Yip3S (Yip3 Short)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    545268..545877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182883.1 → NP_014354.2  TPA: Yip3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014354.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1D5, P53633
    UniProtKB/TrEMBL
    A6ZS34, B3LNQ6, C7GLV6, C8ZGI4, G2WM59, N1NXL4
    Conserved Domains (1) summary
    COG5130
    Location:1 → 176
    YIP3; Prenylated rab acceptor 1 and related proteins [Intracellular trafficking and secretion / Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53633.2

Gene LinkOut

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