HEF3 translation elongation factor EF-3 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: HEF3
Official Full Name: translation elongation factor EF-3
Primary source: SGD:S000004959
Locus tag: YNL014W
See related: AllianceGenome:SGD:S000004959; FungiDB:YNL014W; VEuPathDB:YNL014W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: ZRG7
Summary: Enables ATP hydrolysis activity and translation elongation factor activity. Involved in translational elongation. Located in cytosolic ribosome. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XIV - NC_001146.8 Genomic Context describing neighboring genes

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Eukaryotic Elongation Factor 3 Protects Saccharomyces cerevisiae Yeast from Oxidative Stress.
Title: Eukaryotic Elongation Factor 3 Protects Saccharomyces cerevisiae Yeast from Oxidative Stress.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IBA Inferred from Biological aspect of Ancestor more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	IDA Inferred from Direct Assay more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IGI Inferred from Genetic Interaction more info	PubMed
enables translation elongation factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosolic ribosome	IPI Inferred from Physical Interaction more info	PubMed

NP_014384.3

Translational elongation factor EF-3; member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells; HEF3 has a paralog, YEF3, that arose from the whole genome duplication

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The following sections contain reference sequences that belong to a specific genome build. Explain