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BBP1 Bbp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855820, updated on 2-Nov-2024

Summary

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Official Symbol
BBP1
Official Full Name
Bbp1p
Primary source
SGD:S000006176
Locus tag
YPL255W
See related
AllianceGenome:SGD:S000006176; FungiDB:YPL255W; VEuPathDB:YPL255W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables structural molecule activity. Involved in protein localization to spindle pole body and spindle pole body duplication. Located in central plaque of spindle pole body. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See BBP1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (67725..68882)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cyclin CLN2 Neighboring gene Hfi1p Neighboring gene Vik1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yeast mutants that produce a novel type of ascus containing asci instead of spores. Xue Z, et al. Genetics, 1996 Nov. PMID 8913743, Free PMC Article
  2. Requirement for Bbp1p in the proper mitotic functions of Cdc5p in Saccharomyces cerevisiae. Park CJ, et al. Mol Biol Cell, 2004 Apr. PMID 14767068, Free PMC Article
  3. Specific coiled-coil interactions contribute to a global model of the structure of the spindle pole body. Zizlsperger N, et al. J Struct Biol, 2010 May. PMID 20139001
  4. The Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. Schramm C, et al. EMBO J, 2000 Feb 1. PMID 10654940, Free PMC Article
  5. Yeast centrosome components form a noncanonical LINC complex at the nuclear envelope insertion site. Chen J, et al. J Cell Biol, 2019 May 6. PMID 30862629, Free PMC Article

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein localization to spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spindle pole body duplication IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in spindle pole body duplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in central plaque of spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole body IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Bbp1p
NP_015068.1
  • Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    67725..68882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184069.1 → NP_015068.1  TPA: Bbp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015068.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3LKH7, B5VST2, C8ZIC3, D6W3B6, E7KV71, E7QLJ6, Q12365
    UniProtKB/TrEMBL
    N1NW40
    Conserved Domains (2) summary
    pfam15271
    Location:10 → 170
    BBP1_N; Spindle pole body component BBP1, Mps2-binding protein
    pfam15272
    Location:218 → 383
    BBP1_C; Spindle pole body component BBP1, C-terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12365.1

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