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MRPL40 mitochondrial 54S ribosomal protein YmL40 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855930, updated on 18-Sep-2024

Summary

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Official Symbol
MRPL40
Official Full Name
mitochondrial 54S ribosomal protein YmL40
Primary source
SGD:S000006094
Locus tag
YPL173W
See related
AllianceGenome:SGD:S000006094; FungiDB:YPL173W; VEuPathDB:YPL173W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
uL24m
Summary
A structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL24 (mitochondrial ribosomal protein L24). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MRPL40 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (223143..224036)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase SPT14 Neighboring gene Nip100p Neighboring gene protoheme IX farnesyltransferase Neighboring gene NADPH dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The DEAD box protein Mrh4 functions in the assembly of the mitochondrial large ribosomal subunit. De Silva D, et al. Cell Metab, 2013 Nov 5. PMID 24206665, Free PMC Article
  2. Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. Jia L, et al. Eukaryot Cell, 2009 Nov. PMID 19783770, Free PMC Article
  3. High levels of the mitochondrial large ribosomal subunit protein 40 prevent loss of mitochondrial DNA in null mmf1 Saccharomyces cerevisiae cells. Accardi R, et al. Yeast, 2004 May. PMID 15164357
  4. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. Gruschke S, et al. J Biol Chem, 2010 Jun 18. PMID 20404317, Free PMC Article
  5. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. Kaur J, et al. EMBO Rep, 2011 Sep 1. PMID 21779004, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MrpL40, a large ribosomal subunit component, is physically interact with Oxa1.
    Title: Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in intracellular non-membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 54S ribosomal protein YmL40
NP_015152.1
  • Mitochondrial ribosomal protein of the large subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    223143..224036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183987.1 → NP_015152.1  TPA: mitochondrial 54S ribosomal protein YmL40 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015152.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3J5, P36534, Q6B277
    UniProtKB/TrEMBL
    A6ZW80, B3LKQ5, B5VSZ8, C8ZIK5, G2WP09, N1NY13
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36534.2

Gene LinkOut

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