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CQD1 Cqd1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855995, updated on 2-Nov-2024

Summary

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Official Symbol
CQD1
Official Full Name
Cqd1p
Primary source
SGD:S000006030
Locus tag
YPL109C
See related
AllianceGenome:SGD:S000006030; FungiDB:YPL109C; VEuPathDB:YPL109C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MCO76
Summary
Acts upstream of or within mitochondrion organization and phospholipid homeostasis. Located in mitochondrial inner membrane and mitochondrial inner-outer membrane contact site. Orthologous to human ADCK2 (aarF domain containing kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CQD1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
2
Sequence:
Chromosome: XVI; NC_001148.4 (345264..347389, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene arginase Neighboring gene glycerophosphocholine phosphodiesterase Neighboring gene uncharacterized protein Neighboring gene Dpc25p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae. Kemmerer ZA, et al. Nat Commun, 2021 Aug 6. PMID 34362905, Free PMC Article
  2. Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis. Stefely JA, et al. Mol Cell, 2015 Jan 8. PMID 25498144, Free PMC Article
  3. The UbiB family member Cqd1 forms a novel membrane contact site in mitochondria. Khosravi S, et al. J Cell Sci, 2023 May 15. PMID 37073556, Free PMC Article
  4. Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex. Wysocka M, et al. Exp Cell Res, 2004 Apr 1. PMID 15023545
  5. A hunt for OM45 synthetic petite interactions in Saccharomyces cerevisiae reveals a role for Miro GTPase Gem1p in cristae structure maintenance. Shvetsova A, et al. Microbiologyopen, 2021 Oct. PMID 34713605, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrion organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phospholipid homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner-outer membrane contact site IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cqd1p
NP_015216.3
  • UbiB protein kinase-like family member; mitochondrial inner membrane protein that interacts with outer membrane proteins Por1p and Om14p to form a MICOS-independent mitochondrial contact site; role in mitochondrial organization; contributes to mitochondrial lipid homeostasis; controls the cellular distribution of coenzyme Q (CoQ); contains a potential mitochondrial targeting sequence and predicted transmembrane domain

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    345264..347389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183923.1 → NP_015216.3  TPA: Cqd1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015216.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3Q8, Q02981
    UniProtKB/TrEMBL
    A6ZWE2, B3LKW4, C8ZIS1, G2WP72
    Conserved Domains (1) summary
    cd13971
    Location:200 → 538
    ADCK2-like; aarF domain containing kinase 2 and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02981.2

Gene LinkOut

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