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SNT309 Snt309p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856216, updated on 2-Nov-2024

Summary

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Official Symbol
SNT309
Official Full Name
Snt309p
Primary source
SGD:S000006305
Locus tag
YPR101W
See related
AllianceGenome:SGD:S000006305; FungiDB:YPR101W; VEuPathDB:YPR101W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
NTC25
Summary
Predicted to contribute to first spliceosomal transesterification activity. Involved in mRNA splicing, via spliceosome. Part of Prp19 complex and U2-type catalytic step 1 spliceosome. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SNT309 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (730492..731019)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Tmh18p Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein MRPL51 Neighboring gene ribosomal 60S subunit protein L11A Neighboring gene proteasome core particle subunit beta 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p. Chen HR, et al. Mol Cell Biol, 1998 Apr. PMID 9528791, Free PMC Article
  2. Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing. Chen HR, et al. Proc Natl Acad Sci U S A, 1999 May 11. PMID 10318896, Free PMC Article
  3. Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. Chen CH, et al. J Biol Chem, 2001 Jan 5. PMID 11018040
  4. Thermoconditional modulation of the pleiotropic sensitivity phenotype by the Saccharomyces cerevisiae PRP19 mutant allele pso4-1. Revers LF, et al. Nucleic Acids Res, 2002 Nov 15. PMID 12434004, Free PMC Article
  5. Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. Chen CH, et al. RNA, 2006 May. PMID 16540691, Free PMC Article

See all (57) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to first spliceosomal transesterification activity IC
Inferred by Curator
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Prp19 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U2-type catalytic step 1 spliceosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Snt309p
NP_015426.1
  • Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; interacts physically and genetically with Prp19p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    730492..731019
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184198.1 → NP_015426.1  TPA: Snt309p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015426.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W499, Q06091
    UniProtKB/TrEMBL
    A6ZWY1, B3LK65, B5VTP2, C8ZJC3, G2WPR7, N1NW37
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06091.1

Gene LinkOut

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