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SGE1 Sge1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856327, updated on 2-Nov-2024

Summary

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Official Symbol
SGE1
Official Full Name
Sge1p
Primary source
SGD:S000006402
Locus tag
YPR198W
See related
AllianceGenome:SGD:S000006402; FungiDB:YPR198W; VEuPathDB:YPR198W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
NOR1
Summary
Enables xenobiotic transmembrane transporter activity. Involved in transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SGE1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (934034..935665)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative maltose-responsive transcription factor Neighboring gene Arr1p Neighboring gene Arr2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Saccharomyces cerevisiae MFS superfamily SGE1 gene confers resistance to cationic dyes. Jacquot C, et al. Yeast, 1997 Aug. PMID 9271105
  2. The Sge1 protein of Saccharomyces cerevisiae is a membrane-associated multidrug transporter. Ehrenhofer-Murray AE, et al. Yeast, 1998 Jan 15. PMID 9483795
  3. The Saccharomyces cerevisiae SGE1 gene product: a novel drug-resistance protein within the major facilitator superfamily. Ehrenhofer-Murray AE, et al. Mol Gen Genet, 1994 Aug 2. PMID 8058039
  4. Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast. Higgins DA, et al. Genetics, 2018 Sep. PMID 30045857, Free PMC Article
  5. Isolation and characterization of SGE1: a yeast gene that partially suppresses the gal11 mutation in multiple copies. Amakasu H, et al. Genetics, 1993 Jul. PMID 8349103, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables xenobiotic transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in xenobiotic transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Sge1p
NP_015524.1
  • Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    934034..935665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184295.1 → NP_015524.1  TPA: Sge1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015524.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4J6, P33335, Q05720
    UniProtKB/TrEMBL
    A6ZX70, B3LRH8, B5VTX5, C8ZJM7, N1NW75
    Conserved Domains (1) summary
    cd17502
    Location:24 → 531
    MFS_Azr1_MDR_like; Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P33335.1

Gene LinkOut

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