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AIM17 Aim17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856365, updated on 2-Nov-2024

Summary

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Official Symbol
AIM17
Official Full Name
Aim17p
Primary source
SGD:S000001013
Locus tag
YHL021C
See related
AllianceGenome:SGD:S000001013; FungiDB:YHL021C; VEuPathDB:YHL021C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FMP12
Summary
Predicted to enable dioxygenase activity and metal ion binding activity. Involved in mitochondrion organization. Located in mitochondrion. Orthologous to human BBOX1 (gamma-butyrobetaine hydroxylase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See AIM17 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (64462..65859, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene tRNA-His Neighboring gene DNA topoisomerase (ATP-hydrolyzing) Neighboring gene transcriptional regulator OPI1 Neighboring gene Apm2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Putative mitochondrial α-ketoglutarate-dependent dioxygenase Fmp12 controls utilization of proline as an energy source in Saccharomyces cerevisiae. Nishida I, et al. Microb Cell, 2016 Sep 19. PMID 28357320, Free PMC Article
  2. Mutations of the TATA-binding protein confer enhanced tolerance to hyperosmotic stress in Saccharomyces cerevisiae. Kim NR, et al. Appl Microbiol Biotechnol, 2013 Sep. PMID 23709042
  3. Construction of Saccharomyces cerevisiae strains with enhanced ethanol tolerance by mutagenesis of the TATA-binding protein gene and identification of novel genes associated with ethanol tolerance. Yang J, et al. Biotechnol Bioeng, 2011 Aug. PMID 21437883
  4. Regulation of lipid droplet dynamics in Saccharomyces cerevisiae depends on the Rab7-like Ypt7p, HOPS complex and V1-ATPase. Bouchez I, et al. Biol Open, 2015 May 6. PMID 25948753, Free PMC Article
  5. A Genetic Screen To Identify Genes Influencing the Secondary Redox Couple NADPH/NADP(+) in the Yeast Saccharomyces cerevisiae. Yadav S, et al. G3 (Bethesda), 2020 Jan 7. PMID 31757928, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carnitine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Aim17p
NP_011842.1
  • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    64462..65859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179101.1 → NP_011842.1  TPA: Aim17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011842.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKP4, P23180
    UniProtKB/TrEMBL
    A6ZSN0, C7GIR5, G2WF45, N1P9H9
    Conserved Domains (1) summary
    cd00250
    Location:128 → 448
    CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23180.2

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