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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 856369, updated on 2-Nov-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000001009
Locus tag
YHL017W
See related
AllianceGenome:SGD:S000001009; FungiDB:YHL017W; VEuPathDB:YHL017W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in retrograde transport, endosome to Golgi. Located in clathrin-coated vesicle. Orthologous to human TMEM87A (transmembrane protein 87A) and TMEM87B (transmembrane protein 87B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (70276..71874)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Apm2p Neighboring gene 4a-hydroxytetrahydrobiopterin dehydratase Neighboring gene Dur3p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. Johnston M, et al. Science, 1994 Sep 30. PMID 8091229
  2. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article
  3. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article
  4. The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. Moehle EA, et al. PLoS Genet, 2012. PMID 23209445, Free PMC Article
  5. Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment. Shulist K, et al. Sci Rep, 2017 Sep 12. PMID 28900268, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in clathrin-coated vesicle HDA PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_011846.1
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    70276..71874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179097.1 → NP_011846.1  TPA: uncharacterized protein YHL017W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011846.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKR6, P38745
    UniProtKB/TrEMBL
    B5VJR3, C7GIR9, G2WF49, N1P1E0
    Conserved Domains (1) summary
    pfam06814
    Location:152 → 444
    Lung_7-TM_R; Lung seven transmembrane receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38745.1

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