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PAL2 Pal2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856497, updated on 18-Sep-2024

Summary

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Official Symbol
PAL2
Official Full Name
Pal2p
Primary source
SGD:S000001139
Locus tag
YHR097C
See related
AllianceGenome:SGD:S000001139; FungiDB:YHR097C; VEuPathDB:YHR097C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SCD1
Summary
Located in actin cortical patch and nuclear periphery. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PAL2 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
2
Sequence:
Chromosome: VIII; NC_001140.6 (297385..298609, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene hexose transporter HXT1 Neighboring gene hexose transporter HXT5 Neighboring gene Sfb3p Neighboring gene histone acetyltransferase TRA1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of Suppressor of Clathrin Deficiency-1 (SCD1) and Its Connection to Clathrin-Mediated Endocytosis in Saccharomyces cerevisiae. Moorthy BT, et al. G3 (Bethesda), 2019 Mar 7. PMID 30679249, Free PMC Article
  2. The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway. Brown CR, et al. J Biol Chem, 2010 Jul 23. PMID 20457600, Free PMC Article
  3. Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes. Li Y, et al. Proc Natl Acad Sci U S A, 2014 Aug 5. PMID 25049391, Free PMC Article
  4. TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Muir A, et al. Elife, 2014 Oct 3. PMID 25279700, Free PMC Article
  5. Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I. Matos J, et al. Cell, 2008 Nov 14. PMID 19013276

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phosphorylation of Pal2 by the protein kinases Kin1 and Kin2 modulates HAC1 mRNA splicing in the unfolded protein response in yeast.
    Title: Phosphorylation of Pal2 by the protein kinases Kin1 and Kin2 modulates HAC1 mRNA splicing in the unfolded protein response in yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in actin cortical patch IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pal2p
NP_011965.1
  • Protein involved in clathrin-mediated endocytosis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YHR097C has a paralog, PAL1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    297385..298609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179227.1 → NP_011965.1  TPA: Pal2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011965.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DL47, P38809
    UniProtKB/TrEMBL
    A6ZT05, B3LSL2, C7GLY5, G2WFH1, N1P4L9
    Conserved Domains (1) summary
    pfam08316
    Location:131 → 271
    Pal1; Pal1 cell morphology protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38809.1

Gene LinkOut

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