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PFS1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856591, updated on 11-Sep-2024

Summary

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Official Symbol
PFS1
Primary source
SGD:S000001228
Locus tag
YHR185C
See related
AllianceGenome:SGD:S000001228; FungiDB:YHR185C; VEuPathDB:YHR185C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ADY1
Summary
Involved in ascospore wall assembly. Predicted to be located in cytoplasm; nucleus; and spindle pole body. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (474627..475340, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene phosphogluconate dehydrogenase (decarboxylating) GND1 Neighboring gene Ssp1p Neighboring gene tRNA-Val Neighboring gene ubiquitin-binding TORC1 subunit KOG1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae. Deng C, et al. Mol Biol Cell, 2001 Sep. PMID 11553705, Free PMC Article
  2. Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast. Grabowska E, et al. Mol Microbiol, 2014 May. PMID 24628792
  3. Acetate regulation of spore formation is under the control of the Ras/cyclic AMP/protein kinase A pathway and carbon dioxide in Saccharomyces cerevisiae. Jungbluth M, et al. Eukaryot Cell, 2012 Aug. PMID 22660623, Free PMC Article
  4. Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Petronczki M, et al. Cell, 2006 Sep 22. PMID 16990132
  5. Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity. Dheur S, et al. J Biol Chem, 2005 Jul 1. PMID 15894541

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ascospore wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole body IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pfs1p
NP_012055.3
  • Sporulation protein required for prospore membrane formation; required for prospore membrane formation at selected spindle poles; ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    474627..475340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179316.3 → NP_012055.3  TPA: Pfs1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012055.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLD3, P38872
    UniProtKB/TrEMBL
    A6ZT91, B3LSU6, B5VKB3, C7GRK7, C8Z9Y4, N1P303
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38872.1

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