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IMT4 tRNA-Met [ Saccharomyces cerevisiae S288C ]

Gene ID: 856685, updated on 25-Apr-2024

Summary

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Gene symbol
IMT4
Gene description
tRNA-Met
Primary source
SGD:S000006660
Locus tag
YNCE0006W
See related
AllianceGenome:SGD:S000006660
Gene type
tRNA
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables eukaryotic initiation factor eIF2 binding activity. Predicted to be involved in translational initiation. Part of eukaryotic 43S preinitiation complex and eukaryotic 48S preinitiation complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See IMT4 in Genome Data Viewer
Location:
chromosome: V
Sequence:
Chromosome: V; NC_001137.3 (100133..100204)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene putative pyridoxal kinase BUD16 Neighboring gene uncharacterized protein Neighboring gene H(+)-transporting V0 sector ATPase subunit c Neighboring gene RNA binding protein SNU13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactions between Ty1 retrotransposon RNA and the T and D regions of the tRNA(iMet) primer are required for initiation of reverse transcription in vivo. Friant S, et al. Mol Cell Biol, 1998 Feb. PMID 9447976, Free PMC Article
  2. Identity elements for specific aminoacylation of a tRNA by mammalian lysyl-tRNA synthetase bearing a nonspecific tRNA-interacting factor. Francin M, et al. Biochemistry, 2006 Aug 22. PMID 16906773
  3. An innovative protein expression system using RNA polymerase I for large-scale screening of high-nucleic-acid content Saccharomyces cerevisiae strains. Zeng D, et al. Microb Biotechnol, 2020 Nov. PMID 32854170, Free PMC Article
  4. Rex1p deficiency leads to accumulation of precursor initiator tRNAMet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae. Ozanick SG, et al. Nucleic Acids Res, 2009 Jan. PMID 19042972, Free PMC Article
  5. The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Anderson J, et al. Genes Dev, 1998 Dec 1. PMID 9851972, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • Methionine initiator tRNA (tRNA-Met); predicted by tRNAscan-SE analysis; one of four initiator methionine tRNAs in yeast that are functional for translation

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables eukaryotic initiation factor eIF2 binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables triplet codon-amino acid adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables triplet codon-amino acid adaptor activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IC
Inferred by Curator
more info
 PubMed 
part_of eukaryotic 43S preinitiation complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic 48S preinitiation complex IDA
Inferred from Direct Assay
more info
 PubMed 

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