U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SAP1 putative AAA family ATPase SAP1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856771, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
SAP1
Official Full Name
putative AAA family ATPase SAP1
Primary source
SGD:S000000849
Locus tag
YER047C
See related
AllianceGenome:SGD:S000000849; FungiDB:YER047C; VEuPathDB:YER047C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ATP hydrolysis activity. Located in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4 and nicotine dependence. Orthologous to human FIGNL1 (fidgetin like 1); FIGN (fidgetin, microtubule severing factor); and SPAST (spastin). [provided by Alliance of Genome Resources, Oct 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SAP1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (243810..246503, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Aca1p Neighboring gene Spo73p Neighboring gene Caj1p Neighboring gene tRNA-Gln

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Association of yeast SAP1, a novel member of the 'AAA' ATPase family of proteins, with the chromatin protein SIN1. Liberzon A, et al. FEBS Lett, 1996 Jun 10. PMID 8654588
  2. Elg1, the major subunit of an alternative RFC complex, interacts with SUMO-processing proteins. Parnas O, et al. Cell Cycle, 2011 Sep 1. PMID 21869594
  3. Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. Montpetit B, et al. J Cell Biol, 2006 Aug 28. PMID 16923829, Free PMC Article
  4. Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Chiolo I, et al. Mol Cell Biol, 2005 Jul. PMID 15964827, Free PMC Article
  5. Snx4-assisted vacuolar targeting of transcription factors defines a new autophagy pathway for controlling ATG expression. Hanley SE, et al. Autophagy, 2021 Nov. PMID 33678121, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
putative AAA family ATPase SAP1
NP_010966.1
  • Putative ATPase of the AAA family; interacts with the Sin1p transcriptional repressor in the two-hybrid system

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    243810..246503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178938.1 → NP_010966.1  TPA: putative AAA family ATPase SAP1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010966.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLU8, P39955
    UniProtKB/TrEMBL
    G2WCT1
    Conserved Domains (2) summary
    COG0464
    Location:557 → 890
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam05109
    Location:353 → 543
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39955.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools