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PCL6 Pcl6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856787, updated on 29-Jun-2024

Summary

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Gene symbol
PCL6
Gene description
Pcl6p
Primary source
FungiDB:YER059W
Locus tag
YER059W
See related
SGD:S000000861; AllianceGenome:SGD:S000000861; VEuPathDB:YER059W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in regulation of glycogen biosynthetic process and regulation of glycogen catabolic process. Predicted to be located in cytoplasm. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PCL6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (272624..273886)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene putative isoleucine biosynthesis protein HMF1 Neighboring gene Pet117p Neighboring gene purine-cytosine permease Neighboring gene purine-cytosine permease

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Binding to Elongin C inhibits degradation of interacting proteins in yeast. Hyman LE, et al. J Biol Chem, 2002 May 3. PMID 11864988
  2. Analysis of phosphorylation of YJL084c, a yeast protein. Shi XZ, et al. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai), 2002 Jul. PMID 12098764
  3. Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo. Tan YS, et al. J Biol Chem, 2003 Jan 3. PMID 12407105
  4. The yeast cyclins Pc16p and Pc17p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p. Wang Z, et al. FEBS Lett, 2001 Oct 12. PMID 11602261
  5. Novel roles for elongin C in yeast. Jackson T, et al. Biochim Biophys Acta, 2000 Apr 25. PMID 10760578

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cyclin-dependent protein serine/threonine kinase regulator activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of glycogen biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of glycogen catabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
  
part_of cyclin-dependent protein kinase holoenzyme complex TAS
Traceable Author Statement
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pcl6p
NP_010980.1
  • Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding; PCL6 has a paralog, PCL7, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    272624..273886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178950.1 → NP_010980.1  TPA: Pcl6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010980.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLW3, P40038
    UniProtKB/TrEMBL
    A0A8H8ULS5, A6ZR12, B3LS74, B5VHJ0, C7GWI8, C8Z765
    Conserved Domains (1) summary
    pfam08613
    Location:170 → 388
    Cyclin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40038.1

Gene LinkOut

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