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FCY21 purine-cytosine permease [ Saccharomyces cerevisiae S288C ]

Gene ID: 856788, updated on 2-Nov-2024

Summary

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Official Symbol
FCY21
Official Full Name
purine-cytosine permease
Primary source
SGD:S000000862
Locus tag
YER060W
See related
AllianceGenome:SGD:S000000862; FungiDB:YER060W; VEuPathDB:YER060W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables nucleobase transmembrane transporter activity. Involved in cytosine transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See FCY21 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (274567..276153)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Pet117p Neighboring gene Pcl6p Neighboring gene purine-cytosine permease Neighboring gene fatty acid synthase CEM1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New plasmid system to select for Saccharomyces cerevisiae purine-cytosine permease affinity mutants. Wagner R, et al. J Bacteriol, 2001 Jul. PMID 11418581, Free PMC Article
  2. Various cytosine/adenine permease homologues are involved in the toxicity of 5-fluorocytosine in Saccharomyces cerevisiae. Paluszynski JP, et al. Yeast, 2006 Jul 15. PMID 16845689
  3. New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1. Cocklin R, et al. Genetics, 2011 Mar. PMID 21196523, Free PMC Article
  4. Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Styles EB, et al. Cell Syst, 2016 Sep 28. PMID 27617677, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome V. Dietrich FS, et al. Nature, 1997 May 29. PMID 9169868, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables nucleobase transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleobase transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytosine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytosine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in purine-containing compound transmembrane transport ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
purine-cytosine permease
NP_010981.3
  • Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    274567..276153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178951.3 → NP_010981.3  TPA: purine-cytosine permease [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010981.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLW4, P40039
    UniProtKB/TrEMBL
    A6ZR13, B5VHJ1, C7GWI7, G2WCU7, N1P4V4
    Conserved Domains (1) summary
    COG1457
    Location:62 → 528
    CodB; Purine-cytosine permease or related protein [Nucleotide transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40039.2

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