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VHR2 Vhr2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856793, updated on 17-May-2024

Summary

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Gene symbol
VHR2
Gene description
Vhr2p
Primary source
FungiDB:YER064C
Locus tag
YER064C
See related
SGD:S000000866; AllianceGenome:SGD:S000000866; VEuPathDB:YER064C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable DNA binding activity. Involved in regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See VHR2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (282705..284222, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene glycerol-1-phosphatase HOR2 Neighboring gene Tho1p Neighboring gene isocitrate lyase 1 Neighboring gene tRNA-Ser

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Positive and negative regulation of squalene synthase (ERG9), an ergosterol biosynthetic gene, in Saccharomyces cerevisiae. Kennedy MA, et al. Biochim Biophys Acta, 2001 Jan 26. PMID 11342098
  2. TORC1 ensures membrane trafficking of Tat2 tryptophan permease via a novel transcriptional activator Vhr2 in budding yeast. Daicho K, et al. Cell Signal, 2020 Apr. PMID 31954176
  3. Lsm12 Mediates Deubiquitination of DNA Polymerase η To Help Saccharomyces cerevisiae Resist Oxidative Stress. Yao R, et al. Appl Environ Microbiol, 2019 Jan 1. PMID 30366994, Free PMC Article
  4. The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. Kochan DZ, et al. J Cell Sci, 2021 Aug 1. PMID 34350963, Free PMC Article
  5. Whi3, an S. cerevisiae RNA-binding protein, is a component of stress granules that regulates levels of its target mRNAs. Holmes KJ, et al. PLoS One, 2013. PMID 24386330, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vhr2p
NP_010986.1
  • Non-essential nuclear protein; null mutation has global effects on transcription; VHR2 has a paralog, VHR1, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    282705..284222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178955.1 → NP_010986.1  TPA: Vhr2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010986.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLW9, P40041
    UniProtKB/TrEMBL
    A0A8H8ULT1, A6ZR18, B3LS78
    Conserved Domains (1) summary
    pfam04001
    Location:22 → 103
    Vhr1; Transcription factor Vhr1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40041.1

Gene LinkOut

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