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hsaD 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase [ Nocardia terpenica ]

Gene ID: 88356463, updated on 28-Feb-2024

Summary

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Gene symbol
hsaD
Gene description
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
Locus tag
CRH09_RS03310
Gene type
protein coding
Organism
Nocardia terpenica (strain: NC_YFY_NT001, nat-host: Homo sapiens)
Lineage
Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae; Nocardia
Also known as
bphD
Old locus tag
CRH09_03310
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Genomic context

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NZ_CP023778.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase reductase subunit Neighboring gene iron-dependent extradiol dioxygenase HsaC Neighboring gene 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase oxygenase subunit Neighboring gene Rieske 2Fe-2S domain-containing protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP023778.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism. Lack NA, et al. J Biol Chem, 2010 Jan 1. PMID 19875455, Free PMC Article
  2. Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis. Lack N, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Jan 1. PMID 18097091, Free PMC Article
  3. Diversity of 2,3-dihydroxybiphenyl dioxygenase genes in a strong PCB degrader, Rhodococcus sp. strain RHA1. Sakai M, et al. J Biosci Bioeng, 2002. PMID 16233225
  4. A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Van der Geize R, et al. Proc Natl Acad Sci U S A, 2007 Feb 6. PMID 17264217, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
WP_098692678.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP023778.1 Reference assembly

    Range
    698310..699188 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_098692678.1 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase [Nocardia terpenica]

    UniProtKB/TrEMBL
    A0A291RDH3
Nucleotide Protein
Heading Accession and Version