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metG methionine--tRNA ligase [ Methanohalophilus mahii DSM 5219 ]

Gene ID: 8982300, updated on 22-Oct-2024

Summary

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Gene symbol
metG
Gene description
methionine--tRNA ligase
Locus tag
MMAH_RS00845
Gene type
protein coding
Organism
Methanohalophilus mahii DSM 5219 (strain: DSM 5219, culture-collection: DSM:5219, ATCC 35705, OCM 68, type-material: type strain of Methanohalophilus mahii)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanohalophilus
Old locus tag
Mmah_0169
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Genomic context

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Sequence:
NC_014002.1 (198250..200292, complement)

NC_014002.1Genomic Context describing neighboring genes Neighboring gene sodium/glutamate symporter Neighboring gene class IV adenylate cyclase Neighboring gene signal peptide peptidase SppA Neighboring gene SagB/ThcOx family dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_014002.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nakanishi K, et al. Nat Struct Mol Biol, 2005 Oct. PMID 16155581
  2. Selectivity and specificity of substrate binding in methionyl-tRNA synthetase. Datta D, et al. Protein Sci, 2004 Oct. PMID 15388861, Free PMC Article
  3. Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features. Mechulam Y, et al. J Mol Biol, 1999 Dec 17. PMID 10600385
  4. How methionyl-tRNA synthetase creates its amino acid recognition pocket upon L-methionine binding. Serre L, et al. J Mol Biol, 2001 Mar 2. PMID 11243794
  5. Mode of action and biochemical characterization of REP8839, a novel inhibitor of methionyl-tRNA synthetase. Ochsner UA, et al. Antimicrob Agents Chemother, 2005 Oct. PMID 16189106, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
methionine--tRNA ligase
WP_013036647.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_014002.1 Reference assembly

    Range
    198250..200292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_013036647.1 methionine--tRNA ligase [Methanohalophilus mahii]

    See identical proteins and their annotated locations for WP_013036647.1

    UniProtKB/TrEMBL
    D5E953
    Conserved Domains (4) summary
    cd07957
    Location:381 → 502
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:9 → 371
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    PRK00133
    Location:7 → 679
    metG; methionyl-tRNA synthetase; Reviewed
    cd02800
    Location:574 → 680
    tRNA_bind_EcMetRS_like; tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine ...
Nucleotide Protein
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