HGS - hepatocyte growth factor-regulated tyrosine kinase substrate
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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