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SNR18 [ Saccharomyces cerevisiae S288C ]

Gene ID: 9164867, updated on 2-Nov-2024

Summary

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Official Symbol
SNR18
Primary source
SGD:S000007500
Locus tag
YNCA0003W
See related
AllianceGenome:SGD:S000007500
Gene type
ncRNA
RNA name
snoRNA
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable rRNA 2'-O-ribose methylation guide activity. Predicted to be involved in rRNA methylation. Part of box C/D methylation guide snoRNP complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SNR18 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (142367..142468)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene Hsp70 family ATPase SSA1 Neighboring gene translation elongation factor 1 subunit beta Neighboring gene CORVET complex membrane-binding subunit VPS8 Neighboring gene transcription factor TFIIIC subunit TFC3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001133.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unusual C΄/D΄ motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region. van Nues RW, et al. Nucleic Acids Res, 2017 Feb 28. PMID 28204564, Free PMC Article
  2. Processing of the precursors to small nucleolar RNAs and rRNAs requires common components. Petfalski E, et al. Mol Cell Biol, 1998 Mar. PMID 9488433, Free PMC Article
  3. Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly. Rothé B, et al. Nucleic Acids Res, 2014 Feb. PMID 24234454, Free PMC Article
  4. Synthesis and assembly of the box C+D small nucleolar RNPs. Lafontaine DL, et al. Mol Cell Biol, 2000 Apr. PMID 10733567, Free PMC Article
  5. Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stability. Lafontaine DL, et al. RNA, 1999 Mar. PMID 10094313, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • C/D box small nucleolar RNA (snoRNA); commonly referred to as U18; guides 2'-O-methylation of large subunit (LSU) rRNA at positions A649 and C650

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables rRNA 2'-O-ribose methylation guide activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in rRNA methylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of box C/D methylation guide snoRNP complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of box C/D methylation guide snoRNP complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleolus IC
Inferred by Curator
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 Reference assembly

    Range
    142367..142468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_132150.1 RNA Sequence

    Status: REVIEWED

Gene LinkOut

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Molecular Biology Databases
Research Materials