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OPG080 Ribonucleoside-diphosphate reductase (2) [ Monkeypox virus ]

Gene ID: 929053, updated on 18-Aug-2023

Summary

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Gene symbol
OPG080
Gene description
Ribonucleoside-diphosphate reductase (2)
Locus tag
MPXV_gp060
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Monkeypox virus (strain: Zaire-96-I-16, nat-host: Homo sapiens)
Lineage
Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus
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Genomic context

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Sequence:
NC_003310.1 (61976..64291, complement)

NC_003310.1Genomic Context describing neighboring genes Neighboring gene IMV membrane protein I2 Neighboring gene DNA-binding phosphoprotein (2) Neighboring gene IMV membrane protein I5 Neighboring gene Telomere-binding protein Neighboring gene Viral core cysteine proteinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003310.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human monkeypox and smallpox viruses: genomic comparison. Shchelkunov SN, et al. FEBS Lett, 2001 Nov 30. PMID 11734207, Free PMC Article
  2. Ancient Gene Capture and Recent Gene Loss Shape the Evolution of Orthopoxvirus-Host Interaction Genes. Senkevich TG, et al. mBio, 2021 Aug 31. PMID 34253028, Free PMC Article
  3. Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO). Zmasek CM, et al. Virology, 2019 Mar. PMID 30660046, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
Ribonucleoside-diphosphate reductase (2)
NP_536492.1
  • Taxonomic breadth: chordopoxvirinae; Old product: I4L; ribonucleotide reductase, large subunit, R1; similar to VACV-WR I4L and VACV-Cop I4L

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003310.1 Reference assembly

    Range
    61976..64291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_536492.1 Ribonucleoside-diphosphate reductase (2) [Monkeypox virus]

    See identical proteins and their annotated locations for NP_536492.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q3I8U9, Q8V515
    Conserved Domains (3) summary
    cd01679
    Location:167 → 739
    RNR_I; Class I ribonucleotide reductase
    PLN02437
    Location:1 → 770
    PLN02437; ribonucleoside--diphosphate reductase large subunit
    pfam03477
    Location:1 → 89
    ATP-cone; ATP cone domain
Protein Accession Links
GenPept Link UniProtKB Link
AAL40523.1

Gene LinkOut

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