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Pcdhb17 protocadherin beta 17 [ Mus musculus (house mouse) ]

Gene ID: 93888, updated on 2-Nov-2024

Summary

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Official Symbol
Pcdhb17provided by MGI
Official Full Name
protocadherin beta 17provided by MGI
Primary source
MGI:MGI:2136754
See related
Ensembl:ENSMUSG00000046387 AllianceGenome:MGI:2136754
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PcdhbQ; Pcdhb16; mKIAA1621
Summary
Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Is expressed in brain and embryo. Orthologous to human PCDHB16 (protocadherin beta 16). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Pcdhb17 in Genome Data Viewer
Location:
18 B3; 18 19.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (37618040..37621345)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (37485021..37488290)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene protocadherin alpha 4B Neighboring gene predicted gene, 38666 Neighboring gene predicted gene, 38667 Neighboring gene protocadherin beta 15 Neighboring gene protocadherin beta 16 Neighboring gene protocadherin beta 18 Neighboring gene protocadherin beta 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A unique role of cohesin-SA1 in gene regulation and development. Remeseiro S, et al. EMBO J, 2012 May 2. PMID 22415368, Free PMC Article
  2. Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Alvarez-Saavedra M, et al. Nat Commun, 2014 Jun 20. PMID 24946904, Free PMC Article
  3. Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome. Remeseiro S, et al. Biochim Biophys Acta, 2013 Dec. PMID 23920377, Free PMC Article
  4. Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice. Xu L, et al. Sci Adv, 2021 Jan. PMID 33523829, Free PMC Article
  5. Gamma protocadherins are required for survival of spinal interneurons. Wang X, et al. Neuron, 2002 Dec 5. PMID 12467588

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protocadherin beta-16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053142.4 → NP_444372.2  protocadherin beta-16 precursor

    See identical proteins and their annotated locations for NP_444372.2

    Status: VALIDATED

    Source sequence(s)
    AC020967
    Consensus CDS
    CCDS29183.1
    UniProtKB/TrEMBL
    Q91VD8, Q925L4
    Related
    ENSMUSP00000055072.5, ENSMUST00000053856.6
    Conserved Domains (3) summary
    cd11304
    Location:246 → 343
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam08266
    Location:33 → 112
    Cadherin_2; Cadherin-like
    pfam16492
    Location:687 → 770
    Cadherin_C_2; Cadherin cytoplasmic C-terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    37618040..37621345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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