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rimK ribosomal protein S6 modification protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945484, updated on 10-Oct-2024

Summary

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Official Symbol
rimK
Official Full Name
ribosomal protein S6 modification protein
Primary source
ECOCYC:EG10852
Locus tag
b0852
See related
ASAP:ABE-0002903
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0843; nek
Summary
RimK is required for wild-type post-translational addition of C-terminal glutamic acid residues to ribosomal protein S6 (RpsF) . [More information is available at EcoCyc: EG10852].
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Genomic context

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Sequence:
NC_000913.3 (891967..892869)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene reduced glutaredoxin 1 Neighboring gene DUF1418 domain-containing protein YbjC Neighboring gene NADPH-dependent nitro/quinone reductase NfsA Neighboring gene protein YbjN Neighboring gene putrescine ABC transporter periplasmic binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Poly-alpha-glutamic acid synthesis using a novel catalytic activity of RimK from Escherichia coli K-12. Kino K, et al. Appl Environ Microbiol, 2011 Mar. PMID 21278279, Free PMC Article
  2. Coresistance to neomycin and kanamycin by mutations in an Escherichia coli locus that affects ribosomes. Apirion D, et al. J Bacteriol, 1968 Sep. PMID 4895052, Free PMC Article
  3. Isolation and characterization of mutants of Escherichia coli K12 resistant to the new aminoglycoside antibiotic, amikacin. Hull R, et al. J Gen Microbiol, 1976 Jun. PMID 781182
  4. Oligoglutamylation of E. coli ribosomal protein S6 is under growth phase control. Pletnev PI, et al. Biochimie, 2019 Dec. PMID 31520657
  5. Genome-wide screening with hydroxyurea reveals a link between nonessential ribosomal proteins and reactive oxygen species production. Nakayashiki T, et al. J Bacteriol, 2013 Mar. PMID 23292777, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. S6 modification is regulated solely via the rate of ribosome biosynthesis at limiting concentration of RimK enzyme.
    Title: Oligoglutamylation of E. coli ribosomal protein S6 is under growth phase control.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ribosomal S6-glutamic acid ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosomal S6-glutamic acid ligase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ribosomal S6-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in C-terminal protein amino acid modification IEA
Inferred from Electronic Annotation
more info
  
involved_in SOS response IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within SOS response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ribosomal protein S6 modification protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    891967..892869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415373.1 ribosomal protein S6 modification protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415373.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7ECI2, A0A8S7X4W2, A0AAE9PWQ0, A0AAQ2LRM6
    Conserved Domains (1) summary
    PRK10446
    Location:1 → 300
    PRK10446; 30S ribosomal protein S6--L-glutamate ligase
Nucleotide Protein
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