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flgL flagellar hook-filament junction protein 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945646, updated on 10-Oct-2024

Summary

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Official Symbol
flgL
Official Full Name
flagellar hook-filament junction protein 2
Primary source
ECOCYC:EG11545
Locus tag
b1083
See related
ASAP:ABE-0003666
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1068; flaT
Summary
Overexpression causes mucoidy, decreases the amount of biofilm formed, and prevents flagella formation. [More information is available at EcoGene: EG11545]. Experiments in Salmonella typhimurium using antibodies against the flagellar proteins FlgK and FlgL identify them as junction proteins which connect the filament to the hook . [More information is available at EcoCyc: EG11545].
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Genomic context

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Sequence:
NC_000913.3 (1140033..1140986)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene flagellar P-ring protein Neighboring gene putative peptidoglycan hydrolase FlgJ Neighboring gene flagellar hook-filament junction protein 1 Neighboring gene ncRNA Neighboring gene ribonuclease E Neighboring gene DUF2655 domain-containing protein YceQ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and analysis of the entire Escherichia coli ams gene. ams is identical to hmp1 and encodes a 114 kDa protein that migrates as a 180 kDa protein. Casarégola S, et al. J Mol Biol, 1992 Nov 5. PMID 1447789
  2. Localization and stoichiometry of hook-associated proteins within Salmonella typhimurium flagella. Ikeda T, et al. J Bacteriol, 1987 Mar. PMID 3546266, Free PMC Article
  3. Assigning protein functions by comparative genome analysis: protein phylogenetic profiles. Pellegrini M, et al. Proc Natl Acad Sci U S A, 1999 Apr 13. PMID 10200254, Free PMC Article
  4. Genetic analysis of Escherichia coli K-12 region I flagellar mutants. Komeda Y, et al. J Bacteriol, 1977 Sep. PMID 330498, Free PMC Article
  5. Genes for the hook-basal body proteins of the flagellar apparatus in Escherichia coli. Komeda Y, et al. J Bacteriol, 1978 May. PMID 350831, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in bacterial-type flagellum-dependent cell motility IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in bacterial-type flagellum IEA
Inferred from Electronic Annotation
more info
  
located_in bacterial-type flagellum hook IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
flagellar hook-filament junction protein 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1140033..1140986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415601.1 flagellar hook-filament junction protein 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415601.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAQ2LX80
    Conserved Domains (1) summary
    PRK08027
    Location:1 → 317
    flgL; flagellar hook-filament junction protein FlgL
Nucleotide Protein
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