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ghoS antitoxin of the GhoTS toxin-antitoxin system [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948646, updated on 19-Sep-2024

Summary

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Official Symbol
ghoS
Official Full Name
antitoxin of the GhoTS toxin-antitoxin system
Primary source
ECOCYC:G7830
Locus tag
b4128
See related
ASAP:ABE-0013518
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4121; yjdK
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Genomic context

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Sequence:
NC_000913.3 (4352584..4352880)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF06902 family protein YjdI Neighboring gene putative N-acetyltransferase YjdJ Neighboring gene toxin of the GhoTS toxin-antitoxin system Neighboring gene lysine--tRNA ligase/Ap4A synthetase/Ap3A synthetase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress. Cheng HY, et al. Environ Microbiol, 2014 Jun. PMID 24373067
  2. A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS. Wang X, et al. Nat Chem Biol, 2012 Oct. PMID 22941047, Free PMC Article
  3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
  4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The GhoT/GhoS toxin/antitoxin system protects the cell from antimicrobials.
    Title: Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables RNA endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
antitoxin of the GhoTS toxin-antitoxin system

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4352584..4352880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418552.1 antitoxin of the GhoTS toxin-antitoxin system [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418552.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9ALZ8
    Conserved Domains (1) summary
    pfam11080
    Location:8 → 94
    GhoS; Endoribonuclease GhoS
Nucleotide Protein
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Gene LinkOut

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