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MARF1 meiosis regulator and mRNA stability factor 1 [ Homo sapiens (human) ]

Gene ID: 9665, updated on 2-Nov-2024

Summary

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Official Symbol
MARF1provided by HGNC
Official Full Name
meiosis regulator and mRNA stability factor 1provided by HGNC
Primary source
HGNC:HGNC:29562
See related
Ensembl:ENSG00000166783 MIM:614593; AllianceGenome:HGNC:29562
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LKAP; LMKB; PPP1R34; KIAA0430
Summary
This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010]
Expression
Ubiquitous expression in lymph node (RPKM 15.3), ovary (RPKM 15.0) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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See MARF1 in Genome Data Viewer
Location:
16p13.11
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (15594387..15643154, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (15599246..15648059, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (15688244..15737011, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MPV17L-BMERB1 readthrough Neighboring gene ReSE screen-validated silencer GRCh37_chr16:15506027-15506244 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:15528749-15529371 Neighboring gene MPV17 mitochondrial inner membrane protein like Neighboring gene bMERB domain containing 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr16:15587399-15588598 Neighboring gene Sharpr-MPRA regulatory region 1380 Neighboring gene uncharacterized LOC105371102 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:15603978-15604478 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:15607777-15607948 Neighboring gene NANOG hESC enhancer GRCh37_chr16:15632973-15633474 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:15636050-15636595 Neighboring gene Sharpr-MPRA regulatory region 9672 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:15673003-15673503 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:15680941-15681442 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr16:15684383-15685582 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr16:15693082-15694281 Neighboring gene Sharpr-MPRA regulatory region 10508 Neighboring gene uncharacterized LOC124903649 Neighboring gene microRNA 6506 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:15743803-15744304 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:15744305-15744804 Neighboring gene Sharpr-MPRA regulatory region 7034 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:15766651-15767392 Neighboring gene microRNA 484 Neighboring gene Sharpr-MPRA regulatory region 12074 Neighboring gene nudE neurodevelopment protein 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:15814393-15815196 Neighboring gene myosin heavy chain 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. P-bodies directly regulate MARF1-mediated mRNA decay in human cells. Brothers WR, et al. Nucleic Acids Res, 2022 Jul 22. PMID 35801873, Free PMC Article
  2. A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay. Brothers WR, et al. Elife, 2020 Jun 8. PMID 32510323, Free PMC Article
  3. Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Dunster K, et al. Clin Exp Immunol, 2005 Jun. PMID 15932519, Free PMC Article
  4. LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression. Bloch DB, et al. PLoS One, 2014. PMID 24755989, Free PMC Article
  5. Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs. Nishimura T, et al. Nucleic Acids Res, 2018 Dec 14. PMID 30364987, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. P-bodies directly regulate MARF1-mediated mRNA decay in human cells.
    Title: P-bodies directly regulate MARF1-mediated mRNA decay in human cells.
  2. A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.
    Title: A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.
  3. Human MARF1 is an endoribonuclease that interacts with the DCP1:DCP2 decapping complex and degrades target mRNAs.
    Title: Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.
  4. LMKB is the first protein identified to date that interacts with this portion of Ge-1. LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L.
    Title: LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables CCR4-NOT complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA nuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
  
involved_in female meiotic nuclear division ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in oogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
  
located_in membrane HDA PubMed 
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
meiosis regulator and mRNA stability factor 1
Names
limkain-b1
meiosis arrest female 1
meiosis arrest female protein 1
protein phosphatase 1, regulatory subunit 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021407.1 RefSeqGene

    Range
    5013..53780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184998.2 → NP_001171927.1  meiosis regulator and mRNA stability factor 1 isoform 2

    See identical proteins and their annotated locations for NP_001171927.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) differs in sequence but is the same length as isoform 1.
    Source sequence(s)
    AB007890, BC064914, BC144514, DB360504
    Consensus CDS
    CCDS53990.1
    UniProtKB/TrEMBL
    G8JLP4
    Related
    ENSP00000450309.1, ENST00000551742.5
    Conserved Domains (12) summary
    cd09977
    Location:876 → 937
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1004 → 1074
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1100 → 1171
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1176 → 1247
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1260 → 1330
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1336 → 1406
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1412 → 1484
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1487 → 1562
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:776 → 872
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:509 → 581
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:787 → 875
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  2. NM_001184999.2 → NP_001171928.1  meiosis regulator and mRNA stability factor 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1. This results in a shorter isoform (3), compared to isoform 1.
    Source sequence(s)
    AB007890, AC026401, BC064914, BC144515, DB360504
    Consensus CDS
    CCDS55991.1
    UniProtKB/TrEMBL
    G8JLP4
    Related
    ENSP00000449376.1, ENST00000548025.5
    Conserved Domains (12) summary
    cd09977
    Location:873 → 934
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1001 → 1071
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1097 → 1168
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1173 → 1244
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1257 → 1327
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1333 → 1403
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1409 → 1481
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1484 → 1559
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:349 → 491
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:773 → 869
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:507 → 579
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:784 → 872
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  3. NM_014647.4 → NP_055462.2  meiosis regulator and mRNA stability factor 1 isoform 1

    See identical proteins and their annotated locations for NP_055462.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform (1).
    Source sequence(s)
    AB007890, BC064914, BC137165, DB360504
    Consensus CDS
    CCDS10562.2
    UniProtKB/Swiss-Prot
    A8MSK2, B2RNX2, B4DYY9, B7ZMG1, B7ZMG2, F8VV09, Q6P1R6, Q8WYR2, Q9Y4F3, Q9Y4J9
    UniProtKB/TrEMBL
    G8JLP4
    Related
    ENSP00000379654.3, ENST00000396368.8
    Conserved Domains (12) summary
    cd09977
    Location:876 → 937
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1004 → 1074
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1100 → 1171
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1176 → 1247
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1260 → 1330
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1336 → 1406
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1412 → 1484
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1487 → 1562
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:776 → 872
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:510 → 582
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:787 → 875
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    15594387..15643154 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434955.1 → XP_047290911.1  meiosis regulator and mRNA stability factor 1 isoform X22

  2. XM_047434954.1 → XP_047290910.1  meiosis regulator and mRNA stability factor 1 isoform X21

  3. XM_047434950.1 → XP_047290906.1  meiosis regulator and mRNA stability factor 1 isoform X17

  4. XM_047434948.1 → XP_047290904.1  meiosis regulator and mRNA stability factor 1 isoform X15

  5. XM_047434946.1 → XP_047290902.1  meiosis regulator and mRNA stability factor 1 isoform X13

  6. XM_047434953.1 → XP_047290909.1  meiosis regulator and mRNA stability factor 1 isoform X20

  7. XM_047434949.1 → XP_047290905.1  meiosis regulator and mRNA stability factor 1 isoform X16

  8. XM_017023906.3 → XP_016879395.1  meiosis regulator and mRNA stability factor 1 isoform X14

    UniProtKB/TrEMBL
    G8JLP4

  9. XM_017023905.3 → XP_016879394.1  meiosis regulator and mRNA stability factor 1 isoform X12

    UniProtKB/TrEMBL
    G8JLP4

  10. XM_047434951.1 → XP_047290907.1  meiosis regulator and mRNA stability factor 1 isoform X18

  11. XM_047434945.1 → XP_047290901.1  meiosis regulator and mRNA stability factor 1 isoform X11

    Related
    ENSP00000439819.2, ENST00000540441.6

  12. XM_017023904.3 → XP_016879393.1  meiosis regulator and mRNA stability factor 1 isoform X10

    UniProtKB/TrEMBL
    G8JLP4

  13. XM_017023903.3 → XP_016879392.1  meiosis regulator and mRNA stability factor 1 isoform X9

    UniProtKB/TrEMBL
    G8JLP4

  14. XM_047434943.1 → XP_047290899.1  meiosis regulator and mRNA stability factor 1 isoform X8

  15. XM_047434941.1 → XP_047290897.1  meiosis regulator and mRNA stability factor 1 isoform X6

  16. XM_005255706.3 → XP_005255763.1  meiosis regulator and mRNA stability factor 1 isoform X4

    See identical proteins and their annotated locations for XP_005255763.1

    UniProtKB/TrEMBL
    G8JLP4
    Conserved Domains (12) summary
    cd09977
    Location:875 → 936
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1003 → 1073
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1099 → 1170
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1175 → 1246
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1259 → 1329
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1335 → 1405
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1411 → 1483
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1486 → 1561
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:775 → 871
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:509 → 581
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:786 → 874
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  17. XM_017023902.3 → XP_016879391.1  meiosis regulator and mRNA stability factor 1 isoform X7

    UniProtKB/TrEMBL
    G8JLP4

  18. XM_005255707.3 → XP_005255764.1  meiosis regulator and mRNA stability factor 1 isoform X5

    See identical proteins and their annotated locations for XP_005255764.1

    UniProtKB/TrEMBL
    G8JLP4
    Conserved Domains (11) summary
    cd09977
    Location:867 → 928
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:995 → 1065
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1091 → 1162
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1167 → 1238
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1251 → 1321
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1327 → 1397
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1403 → 1475
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1478 → 1553
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    cd12255
    Location:510 → 582
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:778 → 866
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  19. XM_005255704.2 → XP_005255761.1  meiosis regulator and mRNA stability factor 1 isoform X1

    See identical proteins and their annotated locations for XP_005255761.1

    UniProtKB/TrEMBL
    G8JLP4
    Conserved Domains (12) summary
    cd09977
    Location:877 → 938
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1005 → 1075
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1101 → 1172
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1177 → 1248
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1261 → 1331
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1337 → 1407
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1413 → 1485
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1488 → 1563
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:777 → 873
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:510 → 582
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:788 → 876
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  20. XM_047434947.1 → XP_047290903.1  meiosis regulator and mRNA stability factor 1 isoform X14

  21. XM_047434944.1 → XP_047290900.1  meiosis regulator and mRNA stability factor 1 isoform X8

  22. XM_047434942.1 → XP_047290898.1  meiosis regulator and mRNA stability factor 1 isoform X6

  23. XM_047434939.1 → XP_047290895.1  meiosis regulator and mRNA stability factor 1 isoform X4

  24. XM_017023901.3 → XP_016879390.1  meiosis regulator and mRNA stability factor 1 isoform X3

    UniProtKB/TrEMBL
    G8JLP4
    Conserved Domains (12) summary
    cd09977
    Location:876 → 937
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1004 → 1074
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1100 → 1171
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1176 → 1247
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1260 → 1330
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1336 → 1406
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1412 → 1484
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1487 → 1562
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:776 → 872
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:509 → 581
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:787 → 875
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  25. XM_047434940.1 → XP_047290896.1  meiosis regulator and mRNA stability factor 1 isoform X5

  26. XM_047434938.1 → XP_047290894.1  meiosis regulator and mRNA stability factor 1 isoform X2

    UniProtKB/Swiss-Prot
    A8MSK2, B2RNX2, B4DYY9, B7ZMG1, B7ZMG2, F8VV09, Q6P1R6, Q8WYR2, Q9Y4F3, Q9Y4J9

  27. XM_017023900.3 → XP_016879389.1  meiosis regulator and mRNA stability factor 1 isoform X1

    UniProtKB/TrEMBL
    G8JLP4
    Conserved Domains (12) summary
    cd09977
    Location:877 → 938
    LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
    cd09978
    Location:1005 → 1075
    LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
    cd09979
    Location:1101 → 1172
    LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
    cd09980
    Location:1177 → 1248
    LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
    cd09981
    Location:1261 → 1331
    LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
    cd09982
    Location:1337 → 1407
    LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
    cd09983
    Location:1413 → 1485
    LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
    cd09984
    Location:1488 → 1563
    LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
    cd10910
    Location:352 → 494
    limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
    COG0724
    Location:777 → 873
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12255
    Location:510 → 582
    RRM1_LKAP; RNA recognition motif 1 in Limkain-b1 (LKAP) and similar proteins
    cd12256
    Location:788 → 876
    RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins

  28. XM_047434952.1 → XP_047290908.1  meiosis regulator and mRNA stability factor 1 isoform X19

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187607.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    1252378..1301165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054329172.1 → XP_054185147.1  meiosis regulator and mRNA stability factor 1 isoform X22

  2. XM_054329171.1 → XP_054185146.1  meiosis regulator and mRNA stability factor 1 isoform X21

  3. XM_054329166.1 → XP_054185141.1  meiosis regulator and mRNA stability factor 1 isoform X17

  4. XM_054329164.1 → XP_054185139.1  meiosis regulator and mRNA stability factor 1 isoform X15

  5. XM_054329162.1 → XP_054185137.1  meiosis regulator and mRNA stability factor 1 isoform X13

  6. XM_054329170.1 → XP_054185145.1  meiosis regulator and mRNA stability factor 1 isoform X20

  7. XM_054329165.1 → XP_054185140.1  meiosis regulator and mRNA stability factor 1 isoform X16

  8. XM_054329161.1 → XP_054185136.1  meiosis regulator and mRNA stability factor 1 isoform X14

  9. XM_054329159.1 → XP_054185134.1  meiosis regulator and mRNA stability factor 1 isoform X12

  10. XM_054329167.1 → XP_054185142.1  meiosis regulator and mRNA stability factor 1 isoform X18

  11. XM_054329158.1 → XP_054185133.1  meiosis regulator and mRNA stability factor 1 isoform X11

  12. XM_054329157.1 → XP_054185132.1  meiosis regulator and mRNA stability factor 1 isoform X10

  13. XM_054329156.1 → XP_054185131.1  meiosis regulator and mRNA stability factor 1 isoform X9

  14. XM_054329154.1 → XP_054185129.1  meiosis regulator and mRNA stability factor 1 isoform X8

  15. XM_054329151.1 → XP_054185126.1  meiosis regulator and mRNA stability factor 1 isoform X6

  16. XM_054329147.1 → XP_054185122.1  meiosis regulator and mRNA stability factor 1 isoform X4

  17. XM_054329153.1 → XP_054185128.1  meiosis regulator and mRNA stability factor 1 isoform X7

  18. XM_054329149.1 → XP_054185124.1  meiosis regulator and mRNA stability factor 1 isoform X5

  19. XM_054329143.1 → XP_054185118.1  meiosis regulator and mRNA stability factor 1 isoform X1

  20. XM_054329144.1 → XP_054185119.1  meiosis regulator and mRNA stability factor 1 isoform X1

  21. XM_054329152.1 → XP_054185127.1  meiosis regulator and mRNA stability factor 1 isoform X6

  22. XM_054329146.1 → XP_054185121.1  meiosis regulator and mRNA stability factor 1 isoform X3

  23. XM_054329145.1 → XP_054185120.1  meiosis regulator and mRNA stability factor 1 isoform X2

    UniProtKB/Swiss-Prot
    A8MSK2, B2RNX2, B4DYY9, B7ZMG1, B7ZMG2, F8VV09, Q6P1R6, Q8WYR2, Q9Y4F3, Q9Y4J9

  24. XM_054329148.1 → XP_054185123.1  meiosis regulator and mRNA stability factor 1 isoform X4

  25. XM_054329150.1 → XP_054185125.1  meiosis regulator and mRNA stability factor 1 isoform X5

  26. XM_054329168.1 → XP_054185143.1  meiosis regulator and mRNA stability factor 1 isoform X18

  27. XM_054329155.1 → XP_054185130.1  meiosis regulator and mRNA stability factor 1 isoform X8

  28. XM_054329163.1 → XP_054185138.1  meiosis regulator and mRNA stability factor 1 isoform X14

  29. XM_054329160.1 → XP_054185135.1  meiosis regulator and mRNA stability factor 1 isoform X13

  30. XM_054329169.1 → XP_054185144.1  meiosis regulator and mRNA stability factor 1 isoform X19

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    15599246..15648059 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054314483.1 → XP_054170458.1  meiosis regulator and mRNA stability factor 1 isoform X22

  2. XM_054314482.1 → XP_054170457.1  meiosis regulator and mRNA stability factor 1 isoform X21

  3. XM_054314477.1 → XP_054170452.1  meiosis regulator and mRNA stability factor 1 isoform X17

  4. XM_054314475.1 → XP_054170450.1  meiosis regulator and mRNA stability factor 1 isoform X15

  5. XM_054314473.1 → XP_054170448.1  meiosis regulator and mRNA stability factor 1 isoform X13

  6. XM_054314481.1 → XP_054170456.1  meiosis regulator and mRNA stability factor 1 isoform X20

  7. XM_054314476.1 → XP_054170451.1  meiosis regulator and mRNA stability factor 1 isoform X16

  8. XM_054314472.1 → XP_054170447.1  meiosis regulator and mRNA stability factor 1 isoform X14

  9. XM_054314470.1 → XP_054170445.1  meiosis regulator and mRNA stability factor 1 isoform X12

  10. XM_054314478.1 → XP_054170453.1  meiosis regulator and mRNA stability factor 1 isoform X18

  11. XM_054314469.1 → XP_054170444.1  meiosis regulator and mRNA stability factor 1 isoform X11

  12. XM_054314468.1 → XP_054170443.1  meiosis regulator and mRNA stability factor 1 isoform X10

  13. XM_054314467.1 → XP_054170442.1  meiosis regulator and mRNA stability factor 1 isoform X9

  14. XM_054314465.1 → XP_054170440.1  meiosis regulator and mRNA stability factor 1 isoform X8

  15. XM_054314462.1 → XP_054170437.1  meiosis regulator and mRNA stability factor 1 isoform X6

  16. XM_054314458.1 → XP_054170433.1  meiosis regulator and mRNA stability factor 1 isoform X4

  17. XM_054314464.1 → XP_054170439.1  meiosis regulator and mRNA stability factor 1 isoform X7

  18. XM_054314460.1 → XP_054170435.1  meiosis regulator and mRNA stability factor 1 isoform X5

  19. XM_054314454.1 → XP_054170429.1  meiosis regulator and mRNA stability factor 1 isoform X1

  20. XM_054314455.1 → XP_054170430.1  meiosis regulator and mRNA stability factor 1 isoform X1

  21. XM_054314463.1 → XP_054170438.1  meiosis regulator and mRNA stability factor 1 isoform X6

  22. XM_054314457.1 → XP_054170432.1  meiosis regulator and mRNA stability factor 1 isoform X3

  23. XM_054314456.1 → XP_054170431.1  meiosis regulator and mRNA stability factor 1 isoform X2

  24. XM_054314459.1 → XP_054170434.1  meiosis regulator and mRNA stability factor 1 isoform X4

  25. XM_054314461.1 → XP_054170436.1  meiosis regulator and mRNA stability factor 1 isoform X5

  26. XM_054314479.1 → XP_054170454.1  meiosis regulator and mRNA stability factor 1 isoform X18

  27. XM_054314466.1 → XP_054170441.1  meiosis regulator and mRNA stability factor 1 isoform X8

  28. XM_054314474.1 → XP_054170449.1  meiosis regulator and mRNA stability factor 1 isoform X14

  29. XM_054314471.1 → XP_054170446.1  meiosis regulator and mRNA stability factor 1 isoform X13

  30. XM_054314480.1 → XP_054170455.1  meiosis regulator and mRNA stability factor 1 isoform X19

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_019081.2: Suppressed sequence

    Description
    NM_019081.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y4F3.6 GenPept UniProtKB/Swiss-Prot:Q9Y4F3

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