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Wdr47 WD repeat domain 47 [ Mus musculus (house mouse) ]

Gene ID: 99512, updated on 2-Nov-2024

Summary

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Official Symbol
Wdr47provided by MGI
Official Full Name
WD repeat domain 47provided by MGI
Primary source
MGI:MGI:2139593
See related
Ensembl:ENSMUSG00000040389 AllianceGenome:MGI:2139593
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0893; 1810073M12Rik
Summary
Acts upstream of or within several processes, including detection of hot stimulus involved in thermoception; neuronal stem cell population maintenance; and telencephalon development. Located in several cellular components, including growth cone; microtubule; and neuronal cell body. Is expressed in several structures, including central nervous system; pancreas; respiratory system; sensory organ; and vibrissa. Orthologous to human WDR47 (WD repeat domain 47). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 32.5), CNS E14 (RPKM 23.3) and 16 other tissues See more
Orthologs
human all
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Genomic context

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See Wdr47 in Genome Data Viewer
Location:
3 F3; 3 47.38 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108498302..108553035)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108591223..108645719)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:108365309-108365496 Neighboring gene STARR-positive B cell enhancer ABC_E3459 Neighboring gene transmembrane protein 167B Neighboring gene STARR-positive B cell enhancer ABC_E1629 Neighboring gene STARR-positive B cell enhancer ABC_E6105 Neighboring gene TATA-box binding protein associated factor 13 Neighboring gene 40S ribosomal protein S23 pseudogene Neighboring gene chloride channel CLIC-like 1 Neighboring gene G-protein signalling modulator 2 (AGS3-like, C. elegans) Neighboring gene STARR-positive B cell enhancer ABC_E4575 Neighboring gene AKNA domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules. Liu H, et al. Nat Commun, 2021 Oct 4. PMID 34608154, Free PMC Article
  2. Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats. Wang W, et al. PLoS One, 2012. PMID 22523538, Free PMC Article
  3. Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins. Chen Y, et al. Cell Rep, 2020 Apr 21. PMID 32320668
  4. WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Kannan M, et al. Proc Natl Acad Sci U S A, 2017 Oct 31. PMID 29078390, Free PMC Article
  5. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (2) 
  • Targeted (4)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within anterior commissure morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within autophagy IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within autophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within brain development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cerebral cortex development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cerebral cortex radial glia-guided migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within corpus callosum development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within detection of hot stimulus involved in thermoception IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microtubule cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within motor behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neuron projection development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neuronal stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in growth cone IDA
Inferred from Direct Assay
more info
 PubMed 
located_in microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuron projection IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
WD repeat-containing protein 47
Names
nemitin
neuronal enriched MAP interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358053.1 → NP_001344982.1  WD repeat-containing protein 47 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL683823
    Conserved Domains (4) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:599 → 915
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:611 → 659
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  2. NM_001358054.1 → NP_001344983.1  WD repeat-containing protein 47 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL683823
    Conserved Domains (5) summary
    smart00667
    Location:9 → 42
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:600 → 868
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    cl26927
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3

  3. NM_001358055.1 → NP_001344984.1  WD repeat-containing protein 47 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL683823
    Conserved Domains (5) summary
    smart00667
    Location:9 → 42
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:600 → 868
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    cl26927
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3

  4. NM_181400.3 → NP_852065.2  WD repeat-containing protein 47 isoform 1

    See identical proteins and their annotated locations for NP_852065.2

    Status: VALIDATED

    Source sequence(s)
    AL683823
    Consensus CDS
    CCDS17765.1
    UniProtKB/Swiss-Prot
    A2AGC7, Q80TP4, Q8CGF6
    Related
    ENSMUSP00000057482.9, ENSMUST00000051145.15
    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:600 → 916
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    108498302..108553035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502415.5 → XP_006502478.1  WD repeat-containing protein 47 isoform X9

    See identical proteins and their annotated locations for XP_006502478.1

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:300 → 490
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:607 → 925
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:619 → 667
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  2. XM_006502414.5 → XP_006502477.1  WD repeat-containing protein 47 isoform X9

    See identical proteins and their annotated locations for XP_006502477.1

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:300 → 490
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:607 → 925
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:619 → 667
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  3. XM_036163436.1 → XP_036019329.1  WD repeat-containing protein 47 isoform X10

    Conserved Domains (4) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:607 → 923
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:619 → 667
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  4. XM_006502417.5 → XP_006502480.1  WD repeat-containing protein 47 isoform X11

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:600 → 918
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  5. XM_011240310.3 → XP_011238612.1  WD repeat-containing protein 47 isoform X12

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:293 → 482
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:599 → 917
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:611 → 659
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  6. XM_017319818.3 → XP_017175307.1  WD repeat-containing protein 47 isoform X9

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:300 → 490
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:607 → 925
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:619 → 667
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  7. XM_011240309.3 → XP_011238611.1  WD repeat-containing protein 47 isoform X10

    Conserved Domains (4) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:607 → 923
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:619 → 667
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  8. XM_030252938.2 → XP_030108798.1  WD repeat-containing protein 47 isoform X11

    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:600 → 918
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  9. XM_017319819.2 → XP_017175308.1  WD repeat-containing protein 47 isoform X13

    UniProtKB/Swiss-Prot
    A2AGC7, Q80TP4, Q8CGF6
    Conserved Domains (5) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:293 → 483
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:600 → 916
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:612 → 660
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  10. XM_036163437.1 → XP_036019330.1  WD repeat-containing protein 47 isoform X14

    Conserved Domains (4) summary
    smart00668
    Location:45 → 102
    CTLH; C-terminal to LisH motif
    cd00200
    Location:599 → 915
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:611 → 659
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:13 → 40
    LisH_TPL; LisH-like dimerisation domain

  11. XM_030252937.2 → XP_030108797.1  WD repeat-containing protein 47 isoform X8

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:343 → 532
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:649 → 965
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:661 → 709
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  12. XM_030252939.2 → XP_030108799.1  WD repeat-containing protein 47 isoform X15

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:350 → 540
    Activator_LAG-3; Transcriptional activator LAG-3
    sd00039
    Location:668 → 715
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain
    cl29593
    Location:657 → 756
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  13. XM_030252932.1 → XP_030108792.1  WD repeat-containing protein 47 isoform X1

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:350 → 540
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:657 → 975
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:669 → 717
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  14. XM_030252933.2 → XP_030108793.1  WD repeat-containing protein 47 isoform X3

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:350 → 540
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:657 → 973
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:669 → 717
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  15. XM_011240308.2 → XP_011238610.2  WD repeat-containing protein 47 isoform X2

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:350 → 539
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:656 → 974
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:668 → 716
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  16. XM_036163435.1 → XP_036019328.1  WD repeat-containing protein 47 isoform X4

    Conserved Domains (4) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    cd00200
    Location:656 → 972
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:668 → 716
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  17. XM_030252934.1 → XP_030108794.1  WD repeat-containing protein 47 isoform X5

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:343 → 533
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:650 → 968
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:662 → 710
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  18. XM_030252936.2 → XP_030108796.1  WD repeat-containing protein 47 isoform X7

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:343 → 533
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:650 → 966
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:662 → 710
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

  19. XM_030252935.1 → XP_030108795.1  WD repeat-containing protein 47 isoform X6

    Conserved Domains (5) summary
    smart00668
    Location:95 → 152
    CTLH; C-terminal to LisH motif
    pfam11498
    Location:343 → 532
    Activator_LAG-3; Transcriptional activator LAG-3
    cd00200
    Location:649 → 967
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:661 → 709
    7WD40; WD40 repeat [structural motif]
    pfam17814
    Location:63 → 90
    LisH_TPL; LisH-like dimerisation domain

RNA

  1. XR_004941418.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CGF6.2 GenPept UniProtKB/Swiss-Prot:Q8CGF6

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