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    SCARB1 scavenger receptor class B member 1 [ Homo sapiens (human) ]

    Gene ID: 949, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Results show that SR-B1 mRNA expression increased in response to dexamethasone in primary rat hepatocytes however, the effect was absent or inhibitory in human HepG2 cells and THP-1 macrophages due to low glucocorticoid receptor levels.

    ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines.
    Sporstøl M, Mousavi SA, Eskild W, Roos N, Berg T., Free PMC Article

    01/21/2010
    the c.1119C>T polymorphism is associated with a lower postprandial triglyceride response in the smaller, partially catabolized lipoprotein fraction

    Scavenger receptor class B type I (SCARB1) c.1119C>T polymorphism affects postprandial triglyceride metabolism in men.
    Tanaka T, Delgado-Lista J, Lopez-Miranda J, Perez-Jimenez F, Marin C, Perez-Martinez P, Gomez P, Ordovas JM.

    01/21/2010
    SCARB1 polymorphisms not only show associations with plasma levels of total and low-density lipoprotein cholesterol, respectively, but also with the risk for peripheral arterial disease

    Scavenger receptor class B type I polymorphisms and peripheral arterial disease.
    Ritsch A, Sonderegger G, Sandhofer A, Stanzl U, Tancevski I, Eller P, Schgoer W, Wehinger A, Mueller T, Haltmayer M, Patsch JR.

    01/21/2010
    plays a major role in the clearance of apoptotic cells from the thymus.

    Phosphatidylserine receptor cooperates with high-density lipoprotein receptor in recognition of apoptotic cells by thymic nurse cells.
    Cao WM, Murao K, Imachi H, Hiramine C, Abe H, Yu X, Dobashi H, Wong NC, Takahara J, Ishida T.

    01/21/2010
    HDL-mediated enhancement of HCVpp entry involves a complex interplay between SR-BI, HDL, and HCV envelope glycoproteins

    High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I.
    Voisset C, Callens N, Blanchard E, Op De Beeck A, Dubuisson J, Vu-Dac N.

    01/21/2010
    SR-BI is expressed in a cell-specific fashion in the initial & terminal steps of reverse cholesterol transport. It may be physiologically relevant and have distinct tissue-specific functions.

    Simultaneous expression of apolipoprotein B mRNA editing enzyme and scavenger receptor BI mediated by a therapeutic gene expression system.
    Zhong S, Liu C, Haviland D, Doris PA, Teng BB.

    01/21/2010
    SR-BI transcytosis is regulated by cholesterol and SR-BI has a stationary function on the bile canaliculus

    SR-BI undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized WIF-B cells.
    Harder CJ, Meng A, Rippstein P, McBride HM, McPherson R.

    01/21/2010
    Our data suggest that the LDLr plays a role in regulating cholesterol delivered to the baby from the placenta.

    Influence of maternal lipid profile on placental protein expression of LDLr and SR-BI.
    Ethier-Chiasson M, Duchesne A, Forest JC, Giguère Y, Masse A, Mounier C, Lafond J.

    01/21/2010
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