serum levels of miR-130a, miR-27b and miR-210 may serve as potential biomarkers for early stage atherosclerosis obliterans | Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans. Li T, Cao H, Zhuang J, Wan J, Guan M, Yu B, Li X, Zhang W. | 03/12/2011 |
miR-210 showed marked increases in expression in renal cancer and levels correlated with patient survival. | The VHL-dependent regulation of microRNAs in renal cancer. Neal CS, Michael MZ, Rawlings LH, Van der Hoek MB, Gleadle JM., Free PMC Article | 02/26/2011 |
an important role for miR-210 as a tumor-suppressive microRNA with effects on cancer cell proliferation | MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). Tsuchiya S, Fujiwara T, Sato F, Shimada Y, Tanaka E, Sakai Y, Shimizu K, Tsujimoto G., Free PMC Article | 02/5/2011 |
results demonstrate that miR-210 decreases mitochondrial function and upregulates the glycolysis | Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Chen Z, Li Y, Zhang H, Huang P, Luthra R. | 08/23/2010 |
in head and neck cancer, high levels of miR-210 were associated with locoregional disease recurrence & short overall survival; miR-210 in head and neck cancer correlates with other approaches for assessing hypoxia & is associated with prognosis | hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Gee HE, Camps C, Buffa FM, Patiar S, Winter SC, Betts G, Homer J, Corbridge R, Cox G, West CM, Ragoussis J, Harris AL. | 06/28/2010 |
the hypoxia component of ischemia may limit wound re-epithelialization by stabilizing HIF-1alpha, which induces miR-210 expression, resulting in the down-regulation of the cell-cycle regulatory protein E2F3 | Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Biswas S, Roy S, Banerjee J, Hussain SR, Khanna S, Meenakshisundaram G, Kuppusamy P, Friedman A, Sen CK., Free PMC Article | 05/31/2010 |
miR-210 showed dysregulation in myocardial infarction or fetal hearts when compared to healthy adults. | MicroRNA microarray expression profiling in human myocardial infarction. Bostjancic E, Zidar N, Glavac D., Free PMC Article | 04/12/2010 |
Results identify the iron-sulfur cluster assembly proteins (ISCU1/2) as direct targets for repression by the hypoxia-induced microRNA-210. | MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL, Loscalzo J., Free PMC Article | 01/21/2010 |
MiR-210 overexpression in cancer cell lines bypassed hypoxia-induced cell cycle arrest and partially reversed the hypoxic gene expression signature. | MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Zhang Z, Sun H, Dai H, Walsh RM, Imakura M, Schelter J, Burchard J, Dai X, Chang AN, Diaz RL, Marszalek JR, Bartz SR, Carleton M, Cleary MA, Linsley PS, Grandori C. | 01/21/2010 |
study provides the first evidence for an oncogenic activity of miR-155, miR-203, miR-210 and miR-222 in the development of pancreatic cancer as has been reported for other tumor types | Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival. Greither T, Grochola LF, Udelnow A, Lautenschläger C, Würl P, Taubert H. | 01/21/2010 |
mir-210 may account for at least part of the repressive effect of HIF1alpha on tumor growth. | Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Huang X, Ding L, Bennewith KL, Tong RT, Welford SM, Ang KK, Story M, Le QT, Giaccia AJ., Free PMC Article | 01/21/2010 |
The data suggest that miR-210 might be involved in increased expression of gamma-globin genes in differentiating erythroid cells. | Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression. Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. | 01/21/2010 |