| Nuclear heterogeneous nuclear ribonucleo-protein H expression was related to survival in colorectal cancer. | The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis.
Hope NR, Murray GI. | 04/2/2011 |
| altered function of hnRNP H1/H2 in tumor cells is a novel determinant of aberrant thymidine phosphorylase splicing thereby resulting in acquired chemoresistance to TP-activated fluoropyrimidine anticancer drugs. | Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.
Stark M, Bram EE, Akerman M, Mandel-Gutfreund Y, Assaraf YG., Free PMC Article | 03/26/2011 |
| the G-stretches within exon 9B regulate RAGE alternative splicing via interaction with hnRNP H | Regulation of alternative splicing of the receptor for advanced glycation endproducts (RAGE) through G-rich cis-elements and heterogenous nuclear ribonucleoprotein H.
Ohe K, Watanabe T, Harada S, Munesue S, Yamamoto Y, Yonekura H, Yamamoto H. | 10/23/2010 |
| working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site | hnRNP H1 and intronic G runs in the splicing control of the human rpL3 gene.
Russo A, Siciliano G, Catillo M, Giangrande C, Amoresano A, Pucci P, Pietropaolo C, Russo G. | 06/28/2010 |
| Results suggest that hnRNP H and F are nuclear shuttling proteins whose posttranslational modifications may alter interaction with transportin 1, nuclear localization, and hence function. | A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.
Van Dusen CM, Yee L, McNally LM, McNally MT., Free PMC Article | 06/14/2010 |
| A-Raf prevents cancer cell apoptosis contingent on the expression of the heterogeneous nuclear ribonucleoprotein H (hnRNP H) splice factor, which is required for the correct transcription and expression of a-raf. | Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription.
Rauch J, O'Neill E, Mack B, Matthias C, Munz M, Kolch W, Gires O., Free PMC Article | 04/12/2010 |
| Interactions between different hnRNP proteins bound to distinct locations on a pre-mRNA can change its conformation to affect splicing decisions. | hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection.
Fisette JF, Toutant J, Dugré-Brisson S, Desgroseillers L, Chabot B., Free PMC Article | 02/8/2010 |
| the discovery overexpression of GPD1 and RRBP1 proteins and lack of expression for HNRNPH1 and SERPINB6 proteins which are new candidate biomarkers of colon cancer. | [Colorectal cancer 2D-proteomics: identification of altered protein expression].
Krasnov GS, Oparina NIu, Khankin SL, Mashkova TD, Ershov AN, Zatsepina OG, Karpov VL, Beresten' SF. | 01/21/2010 |
| hnRNPH and F regulate DM20 splicing by recruiting U1snRNP and hnRNPH plays a primary role in DM20 splice site selection in vivo | Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs.
Wang E, Cambi F., Free PMC Article | 01/21/2010 |