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    IL7R interleukin 7 receptor [ Homo sapiens (human) ]

    Gene ID: 3575, updated on 8-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression.

    Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression.
    Semlali A, Almutairi MH, Alamri A, Reddy Parine N, Arafah M, Almadi MA, Aljebreen AM, Alharbi O, Azzam NA, Almutairi R, Alanazi M, Rouabhia M., Free PMC Article

    02/12/2022
    Study on the relationship between the expression of S100A12, CaSR, and IL-7R in the synovium of knee osteoarthritis and angiogenesis.

    Study on the relationship between the expression of S100A12, CaSR, and IL-7R in the synovium of knee osteoarthritis and angiogenesis.
    Xu M, Tu J, Yang Y, Zou W.

    01/22/2022
    CD127 imprints functional heterogeneity to diversify monocyte responses in inflammatory diseases.

    CD127 imprints functional heterogeneity to diversify monocyte responses in inflammatory diseases.
    Zhang B, Zhang Y, Xiong L, Li Y, Zhang Y, Zhao J, Jiang H, Li C, Liu Y, Liu X, Liu H, Ping YF, Zhang QC, Zhang Z, Bian XW, Zhao Y, Hu X., Free PMC Article

    01/15/2022
    Interleukin-7 receptor alpha mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.

    Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
    Almeida ARM, Neto JL, Cachucho A, Euzébio M, Meng X, Kim R, Fernandes MB, Raposo B, Oliveira ML, Ribeiro D, Fragoso R, Zenatti PP, Soares T, de Matos MR, Corrêa JR, Duque M, Roberts KG, Gu Z, Qu C, Pereira C, Pyne S, Pyne NJ, Barreto VM, Bernard-Pierrot I, Clappier E, Mullighan CG, Grosso AR, Yunes JA, Barata JT., Free PMC Article

    01/15/2022
    Expression of KLRG1 and CD127 defines distinct CD8(+) subsets that differentially impact patient outcome in follicular lymphoma.

    Expression of KLRG1 and CD127 defines distinct CD8(+) subsets that differentially impact patient outcome in follicular lymphoma.
    Wu H, Tang X, Kim HJ, Jalali S, Pritchett JC, Villasboas JC, Novak AJ, Yang ZZ, Ansell SM., Free PMC Article

    01/15/2022
    Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis.

    Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis.
    Imani SZH, Hojati Z, Khalilian S, Dehghanian F, Kheirollahi M, Khorrami M, Shaygannejad V, Mirmosayyeb O., Free PMC Article

    01/1/2022
    Mutations that collaborate with IL-7Ra signaling pathways to drive ALL.

    Mutations that collaborate with IL-7Ra signaling pathways to drive ALL.
    Rodrigues GOL, Cramer SD, Winer HY, Hixon JA, Li W, Yunes JA, Durum SK.

    01/1/2022
    Overexpression of wild-type IL-7Ralpha promotes T-cell acute lymphoblastic leukemia/lymphoma.

    Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma.
    Silva A, Almeida ARM, Cachucho A, Neto JL, Demeyer S, de Matos M, Hogan T, Li Y, Meijerink J, Cools J, Grosso AR, Seddon B, Barata JT., Free PMC Article

    12/4/2021
    Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia.

    Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia.
    Guad RM, Taylor-Robinson AW, Wu YS, Gan SH, Zaharan NL, Basu RC, Liew CSL, Wan Md Adnan WAH., Free PMC Article

    10/23/2021
    TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.

    TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.
    Berna R, Mitra N, Lou C, Wan J, Hoffstad O, Wubbenhorst B, Nathanson KL, Margolis DJ., Free PMC Article

    09/18/2021
    Identification of Marker Genes and Pathways in Patients with Primary Biliary Cholangitis.

    Identification of Marker Genes and Pathways in Patients with Primary Biliary Cholangitis.
    Dong X, Yu X, Li H, Kang H.

    09/18/2021
    Single-cell profiling of pediatric T-cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK-STAT signaling pathways.

    Single-cell profiling of pediatric T-cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK-STAT signaling pathways.
    Bonaccorso P, Bugarin C, Buracchi C, Fazio G, Biondi A, Lo Nigro L, Gaipa G.

    08/21/2021
    Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.

    Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.
    Vinoy N, Sheeja N, Kumar S, Biswas L.

    06/26/2021
    IL-7R gene variants are associated with breast cancer susceptibility in Chinese Han women.

    IL-7R gene variants are associated with breast cancer susceptibility in Chinese Han women.
    Wang Z, Wang X, Gao Y, Wang Y, Xu M, Han Q, Zhao X.

    05/29/2021
    IL7RA genetic variants differentially affect IL-7Ralpha expression and alternative splicing: a role in autoimmune and infectious diseases?

    IL7RA genetic variants differentially affect IL-7Rα expression and alternative splicing: a role in autoimmune and infectious diseases?
    Lundtoft C, Seyfarth J, Jacobsen M.

    03/27/2021
    Association of Multiple Sclerosis Phenotypes with Single Nucleotide Polymorphisms of IL7R, LAG3, and CD40 Genes in a Jordanian Population: A Genotype-Phenotype Study.

    Association of Multiple Sclerosis Phenotypes with Single Nucleotide Polymorphisms of IL7R, LAG3, and CD40 Genes in a Jordanian Population: A Genotype-Phenotype Study.
    Al-Eitan L, Qudah MA, Qawasmeh MA., Free PMC Article

    03/27/2021
    Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes.

    Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes.
    Monti P, Vignali D, Ziegler AG, Bonifacio E.

    12/12/2020
    Contribution of IL-7/7R genetic polymorphisms in coronary heart disease in Chinese Han population.

    Contribution of IL-7/7R genetic polymorphisms in coronary heart disease in Chinese Han population.
    Sun Y, Yan J, Zhang J, Wang A, Zou J, Gao C.

    12/12/2020
    Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.

    Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.
    Kim R, Boissel N, Touzart A, Leguay T, Thonier F, Thomas X, Raffoux E, Huguet F, Villarese P, Fourrage C, Passini L, Hunault M, Lepretre S, Chevallier P, Braun T, Lhéritier V, Chantepie S, Maury S, Escoffre M, Tavernier E, Chalandon Y, Graux C, Macintyre E, Ifrah N, Asnafi V, Dombret H, Lhermitte L, on behalf the GRAALL group.

    10/31/2020
    Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker.

    Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker.
    Sheikh A, Abraham N., Free PMC Article

    10/24/2020
    Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation.

    Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation.
    Lev A, Simon AJ, Barel O, Eyal E, Glick-Saar E, Nayshool O, Birk O, Stauber T, Hochberg A, Broides A, Almashanu S, Hendel A, Lee YN, Somech R., Free PMC Article

    10/3/2020
    Engineered IL-7 Receptor Enhances the Therapeutic Effect of AXL-CAR-T Cells on Triple-Negative Breast Cancer.

    Engineered IL-7 Receptor Enhances the Therapeutic Effect of AXL-CAR-T Cells on Triple-Negative Breast Cancer.
    Zhao Z, Li Y, Liu W, Li X., Free PMC Article

    09/26/2020
    Candidate gene association analysis of multiple sclerosis in the Jordanian Arab population: A case-control study.

    Candidate gene association analysis of multiple sclerosis in the Jordanian Arab population: A case-control study.
    Al-Eitan L, Al Qudah M, Al Qawasmeh M.

    09/12/2020
    Interleukin 7 receptor T244I polymorphism and the multiple sclerosis susceptibility: a meta-analysis.

    Interleukin 7 receptor T244I polymorphism and the multiple sclerosis susceptibility: a meta-analysis.
    Sahami-Fard MH, Mozhdeh M, Izadpanah F, Kashani HH, Nezhadi A.

    09/5/2020
    Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.

    Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.
    Abdelrasoul H, Vadakumchery A, Werner M, Lenk L, Khadour A, Young M, El Ayoubi O, Vogiatzi F, Krämer M, Schmid V, Chen Z, Yousafzai Y, Cario G, Schrappe M, Müschen M, Halsey C, Mulaw MA, Schewe DM, Hobeika E, Alsadeq A, Jumaa H., Free PMC Article

    08/29/2020