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    CXCR2 C-X-C motif chemokine receptor 2 [ Homo sapiens (human) ]

    Gene ID: 3579, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Biallelic CXCR2 loss-of-function mutations define a distinct congenital neutropenia entity.

    Biallelic CXCR2 loss-of-function mutations define a distinct congenital neutropenia entity.
    Marin-Esteban V, Youn J, Beaupain B, Jaracz-Ros A, Barlogis V, Fenneteau O, Leblanc T, Bellanger F, Pellet P, Buratti J, Lapillonne H, Bachelerie F, Donadieu J, Bellanné-Chantelot C., Free PMC Article

    04/9/2022
    Prognostic and Immunological Significance of CXCR2 in Ovarian Cancer: A Promising Target for Survival Outcome and Immunotherapeutic Response Assessment.

    Prognostic and Immunological Significance of CXCR2 in Ovarian Cancer: A Promising Target for Survival Outcome and Immunotherapeutic Response Assessment.
    Ji H, Ren M, Liu T, Sun Y., Free PMC Article

    03/12/2022
    Decreased CXCR2 expression on circulating monocytes of colorectal cancer impairs recruitment and induces Re-education of tumor-associated macrophages.

    Decreased CXCR2 expression on circulating monocytes of colorectal cancer impairs recruitment and induces Re-education of tumor-associated macrophages.
    Wang H, Shao Q, Wang J, Zhao L, Wang L, Cheng Z, Yue C, Chen W, Wang H, Zhang Y.

    02/26/2022
    Structural insights into the activation of chemokine receptor CXCR2.

    Structural insights into the activation of chemokine receptor CXCR2.
    Liu K, Shen L, Wu M, Liu ZJ, Hua T.

    02/19/2022
    Impacts of Chemokine (C-X-C Motif) Receptor 2 C1208T Polymorphism on Cancer Susceptibility.

    Impacts of Chemokine (C-X-C Motif) Receptor 2 C1208T Polymorphism on Cancer Susceptibility.
    Zhou J, Wu H, Su QX, Shi XK, Tang BW, Zhao CP, Wang H, Chen XP., Free PMC Article

    02/12/2022
    Association of single nucleotide polymorphisms in CXCR1, CXCR2 and CXCL5 with Behcet disease: a study in the Denizli province of Turkey.

    Association of single nucleotide polymorphisms in CXCR1, CXCR2 and CXCL5 with Behçet disease: a study in the Denizli province of Turkey.
    Arıkan S, Atalay A, Öztürk O, Duygulu Ş, Atalay EÖ.

    02/5/2022
    Bioinformatic analysis for the identification of potential gene interactions and therapeutic targets in atrial fibrillation.

    Bioinformatic analysis for the identification of potential gene interactions and therapeutic targets in atrial fibrillation.
    Yu SD, Yu JY, Guo Y, Liu XY, Liang T, Chen LZ, Chu YP, Zhang HP.

    01/8/2022
    Effect of interleukin-8 receptor B (IL8RB) rs1126579 C>T variation on the risk to cancer.

    Effect of interleukin-8 receptor B (IL8RB) rs1126579 C>T variation on the risk to cancer.
    Zhu L, Tang B, Zhang Z, Wei S, Lv Z, Zhang Y, Yang M., Free PMC Article

    12/25/2021
    Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma.

    Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma.
    Roy S, Kumaravel S, Banerjee P, White TK, O'Brien A, Seelig C, Chauhan R, Ekser B, Bayless KJ, Alpini G, Glaser SS, Chakraborty S., Free PMC Article

    12/25/2021
    [Diagnostic efficiency of determining CXCR1, CXCR2 and hyaluronic acid blood level in non-small cell lung cancer patients].", trans "Diagnosticheskaia effektivnost' opredeleniia urovnia retseptorov CXCR1, CXCR2 i gialuronovoi kisloty v krovi pri nemelkokletochnom rake legkogo.

    [Diagnostic efficiency of determining CXCR1, CXCR2 and hyaluronic acid blood level in non-small cell lung cancer patients].
    Murashka DI, Tahanovich AD, Kauhanka MM, Prokhorova VI, Gotko OV.

    11/22/2021
    C-X-C chemokine receptor 2 (Cxcr2) promotes hepatocellular carcinoma immune evasion via regulating programmed death-ligand 1 (PD-L1).

    C-X-C chemokine receptor 2 (Cxcr2) promotes hepatocellular carcinoma immune evasion via regulating programmed death-ligand 1 (PD-L1).
    Wan Y, Ge K, Zhou W, Lu J, Jia C, Zhu H.

    11/13/2021
    CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer.

    CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer.
    Li E, Yang X, Du Y, Wang G, Chan DW, Wu D, Xu P, Ni P, Xu D, Hu Y., Free PMC Article

    10/30/2021
    CXCL2-CXCR2 axis mediates alphaV integrin-dependent peritoneal metastasis of colon cancer cells.

    CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells.
    Lepsenyi M, Algethami N, Al-Haidari AA, Algaber A, Syk I, Rahman M, Thorlacius H., Free PMC Article

    10/16/2021
    Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies.

    Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies.
    Alam MJ, Xie L, Ang C, Fahimi F, Willingham SB, Kueh AJ, Herold MJ, Mackay CR, Robert R., Free PMC Article

    10/9/2021
    Epithelial-stromal communication via CXCL1-CXCR2 interaction stimulates growth of ovarian cancer cells through p38 activation.

    Epithelial-stromal communication via CXCL1-CXCR2 interaction stimulates growth of ovarian cancer cells through p38 activation.
    Park GY, Pathak HB, Godwin AK, Kwon Y.

    09/25/2021
    Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment.

    Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment.
    Henriques TB, Dos Santos DZ, Dos Santos Guimarães I, Tessarollo NG, Lyra-Junior PCM, Mesquita P, Pádua D, Amaral AL, Cavadas B, Pereira L, Silva IV, Almeida RMDSG, Rangel LBA., Free PMC Article

    07/24/2021
    Distinguishing Sepsis From Infection by Neutrophil Dysfunction: A Promising Role of CXCR2 Surface Level.

    Distinguishing Sepsis From Infection by Neutrophil Dysfunction: A Promising Role of CXCR2 Surface Level.
    Seree-Aphinan C, Vichitkunakorn P, Navakanitworakul R, Khwannimit B., Free PMC Article

    06/26/2021
    Crosstalk between head and neck cancer cells and lymphatic endothelial cells promotes tumor metastasis via CXCL5-CXCR2 signaling.

    Crosstalk between head and neck cancer cells and lymphatic endothelial cells promotes tumor metastasis via CXCL5-CXCR2 signaling.
    Lee BS, Jang JY, Seo C, Kim CH.

    06/19/2021
    Serum cytokines and CXCR2: potential tumour markers in ovarian neoplasms.

    Serum cytokines and CXCR2: potential tumour markers in ovarian neoplasms.
    Micheli DC, Jammal MP, Martins-Filho A, Côrtes JRXM, Souza CN, Nomelini RS, Murta EFC, Tavares-Murta BM.

    06/5/2021
    The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function.

    The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function.
    Urbantat RM, Blank A, Kremenetskaia I, Vajkoczy P, Acker G, Brandenburg S., Free PMC Article

    04/24/2021
    The Clinical Utility of Serum CXCR-2 Assessment in Colorectal Cancer (CRC) Patients.

    The Clinical Utility of Serum CXCR-2 Assessment in Colorectal Cancer (CRC) Patients.
    Pączek S, Łukaszewicz-Zając M, Gryko M, Kulczyńska-Przybik A, Mroczko B.

    04/17/2021
    Lung adenocarcinoma-related TNF-alpha-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.

    Lung adenocarcinoma-related TNF-α-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
    Guo N, Wen Y, Wang C, Kang L, Wang X, Liu X, Soulika AM, Liu B, Zhao M, Han X, Lv P, Xing L, Zhang X, Shen H.

    03/20/2021
    Specific Receptors for the Chemokines CXCR2 and CXCR4 in Pancreatic Cancer.

    Specific Receptors for the Chemokines CXCR2 and CXCR4 in Pancreatic Cancer.
    Litman-Zawadzka A, Łukaszewicz-Zając M, Gryko M, Kulczyńska-Przybik A, Kędra B, Mroczko B., Free PMC Article

    02/27/2021
    IL-8/CXCR2 Signalling Promotes Cell Proliferation in Oesophageal Squamous Cell Carcinoma and Correlates With Poor Prognosis.

    IL-8/CXCR2 Signalling Promotes Cell Proliferation in Oesophageal Squamous Cell Carcinoma and Correlates With Poor Prognosis.
    Inoue M, Takeuchi H, Matsuda S, Nishi T, Fukuda K, Nakamura R, Takahashi T, Wada N, Kawakubo H, Kitagawa Y.

    02/6/2021
    KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma.

    KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma.
    Zhu LM, Zeng D, Lei XC, Huang J, Deng YF, Ji YB, Liu J, Dai FF, Li YZ, Shi DD, Zhu YQ, Dai AG, Wang Z.

    01/23/2021