| Hypoxic lung cancer cell-derived exosomal miR-21 mediates macrophage M2 polarization and promotes cancer cell proliferation through targeting IRF1. | Hypoxic lung cancer cell-derived exosomal miR-21 mediates macrophage M2 polarization and promotes cancer cell proliferation through targeting IRF1.
Jin J, Yu G., Free PMC Article | 08/6/2022 |
| SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1. | SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1.
Shin J, Toyoda S, Nishitani S, Onodera T, Fukuda S, Kita S, Fukuhara A, Shimomura I., Free PMC Article | 07/16/2022 |
| Low expression of PGC-1beta and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1. | Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1.
Laurin KM, Coutu-Beaudry K, Salazar A, Méribout N, Audet-Walsh É, Gravel SP. | 06/18/2022 |
| Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells. | Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells.
Zhang L, Cheng T, Yang H, Chen J, Wen X, Jiang Z, Yi H, Luo Y., Free PMC Article | 03/26/2022 |
| Interferon Gamma-Induced Interferon Regulatory Factor 1 Activates Transcription of HHLA2 and Induces Immune Escape of Hepatocellular Carcinoma Cells. | Interferon Gamma-Induced Interferon Regulatory Factor 1 Activates Transcription of HHLA2 and Induces Immune Escape of Hepatocellular Carcinoma Cells.
Wang R, Guo H, Tang X, Zhang T, Liu Y, Zhang C, Yu H, Li Y. | 03/26/2022 |
| The transcription factor interferon regulatory factor-1 is an endogenous mediator of myocardial ischemia reperfusion injury. | The transcription factor interferon regulatory factor-1 is an endogenous mediator of myocardial ischemia reperfusion injury.
Jiang W, Chen G, Pu J. | 03/19/2022 |
| NF-kappaB-dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity. | NF-κB-dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity.
Ghislat G, Cheema AS, Baudoin E, Verthuy C, Ballester PJ, Crozat K, Attaf N, Dong C, Milpied P, Malissen B, Auphan-Anezin N, Manh TPV, Dalod M, Lawrence T. | 03/12/2022 |
| Identification of molecular subtyping system and four-gene prognostic signature with immune-related genes for uveal melanoma. | Identification of molecular subtyping system and four-gene prognostic signature with immune-related genes for uveal melanoma.
Xia F, Yu Z, Deng A, Gao G., Free PMC Article | 03/5/2022 |
| The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. | The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages.
Gidon A, Louet C, Røst LM, Bruheim P, Flo TH., Free PMC Article | 02/5/2022 |
| IFN-gamma Induces IL-15 Trans-Presentation by Epithelial Cells via IRF1. | IFN-γ Induces IL-15 Trans-Presentation by Epithelial Cells via IRF1.
Kim TS, Rha MS, Shin EC. | 02/5/2022 |
| IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility. | IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility.
Song R, Gao Y, Dozmorov I, Malladi V, Saha I, McDaniel MM, Parameswaran S, Liang C, Arana C, Zhang B, Wakeland B, Zhou J, Weirauch MT, Kottyan LC, Wakeland EK, Pasare C., Free PMC Article | 01/29/2022 |
| IFI44L expression is regulated by IRF-1 and HIV-1. | IFI44L expression is regulated by IRF-1 and HIV-1.
Li Y, Zhang J, Wang C, Qiao W, Li Y, Tan J., Free PMC Article | 12/18/2021 |
| IRF1 regulates the progression of colorectal cancer via interferoninduced proteins. | IRF1 regulates the progression of colorectal cancer via interferon‑induced proteins.
Xu X, Wu Y, Yi K, Hu Y, Ding W, Xing C., Free PMC Article | 11/13/2021 |
| An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation? | An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
Brandt M, Kim-Hellmuth S, Ziosi M, Gokden A, Wolman A, Lam N, Recinos Y, Daniloski Z, Morris JA, Hornung V, Schumacher J, Lappalainen T., Free PMC Article | 11/13/2021 |
| Effect of novel leukemia mutations (K75E & E222K) on interferon regulatory factor 1 and its interaction with DNA: insights from molecular dynamics simulations and docking studies. | Effect of novel leukemia mutations (K75E & E222K) on interferon regulatory factor 1 and its interaction with DNA: insights from molecular dynamics simulations and docking studies.
Kamaraj B, Al-Subaie AM, Ahmad F, Surapaneni KM, Alsamman K. | 10/23/2021 |
| A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells. | A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells.
Zhang MQ, Zhao Q, Zhang JP., Free PMC Article | 10/2/2021 |
| Interferon regulatory factor 1(IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC). | Interferon regulatory factor 1(IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC).
Yan Y, Zheng L, Du Q, Yazdani H, Dong K, Guo Y, Geller DA., Free PMC Article | 09/18/2021 |
| Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN. | Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN.
Loevenich S, Spahn AS, Rian K, Boyartchuk V, Anthonsen MW., Free PMC Article | 09/18/2021 |
| HDAC1 potentiates CD4 + T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus. | HDAC1 potentiates CD4 + T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus.
Chen J, Peng L, Zhao Z, Yang Q, Yin F, Liu M, Luo X, He C, He Y. | 09/11/2021 |
| IRF-1 mediated long non-coding RNA PVT1-214 promotes oxaliplatin resistance of colorectal cancer via miR-128 inhibition. | IRF-1 mediated long non-coding RNA PVT1-214 promotes oxaliplatin resistance of colorectal cancer via miR-128 inhibition.
Tong D, Zou E, Bai L, Ma J, Guo N, Wang H, Jiang L. | 08/21/2021 |
| The Tumor Microenvironment Impairs Th1 IFNgamma Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA. | The Tumor Microenvironment Impairs Th1 IFNγ Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA.
Bernard A, Hibos C, Richard C, Viltard E, Chevrier S, Lemoine S, Melin J, Humblin E, Mary R, Accogli T, Chalmin F, Bruchard M, Peixoto P, Hervouet E, Apetoh L, Ghiringhelli F, Végran F, Boidot R. | 07/31/2021 |
| TLR4/IL-6/IRF1 signaling regulates androgen receptor expression: A potential therapeutic target to overcome taxol resistance in ovarian cancer. | TLR4/IL-6/IRF1 signaling regulates androgen receptor expression: A potential therapeutic target to overcome taxol resistance in ovarian cancer.
Huang SL, Chang TC, Chao CCK, Sun NK. | 07/3/2021 |
| MicroRNA-130b inhibits cerebral ischemia/reperfusion induced cell apoptosis via regulation of IRF1. | MicroRNA-130b inhibits cerebral ischemia/reperfusion induced cell apoptosis via regulation of IRF1.
Liu ZD, Wang Q, Pan DQ, Meng FQ, Li JT, Wang YH. | 07/3/2021 |
| Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity. | Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity.
Rueschenbaum S, Cai C, Schmidt M, Schwarzkopf K, Dittmer U, Zeuzem S, Welsch C, Lange CM., Free PMC Article | 06/19/2021 |
| MiR-134, Mediated by IRF1, Suppresses Tumorigenesis and Progression by Targeting VEGFA and MYCN in Osteosarcoma. | MiR-134, Mediated by IRF1, Suppresses Tumorigenesis and Progression by Targeting VEGFA and MYCN in Osteosarcoma.
Ma Z, Li K, Chen P, Pan Q, Li X, Zhao G. | 05/29/2021 |