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    GIP gastric inhibitory polypeptide [ Homo sapiens (human) ]

    Gene ID: 2695, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    bombesin and nutrients additively stimulate GIP release from GIP/Ins cells.

    Bombesin and nutrients independently and additively regulate hormone release from GIP/Ins cells.
    Li L, Wice BM.

    01/21/2010
    GIP is rapidly degraded into inactive metabolites by the enzyme dipeptidyl-peptidase-IV. (review)

    Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes.
    Gautier JF, Fetita S, Sobngwi E, Salaün-Martin C.

    01/21/2010
    GIP augments glucose-stimulated insulin secretion and acts as an endogenous inhibitor of gastric acid secretion--REVIEW

    Clinical endocrinology and metabolism. Glucose-dependent insulinotropic polypeptide/gastric inhibitory polypeptide.
    Meier JJ, Nauck MA.

    01/21/2010
    Results describe the solution structure of GIP(1-30)amide, the major biologically active fragment of glucose-dependent insulinotropic polypeptide.

    NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.
    Alaña I, Hewage CM, Malthouse JP, Parker JC, Gault VA, O'Harte FP.

    01/21/2010
    Elevated plasma GIP levels are correlated with hyperinsulinemia in the impaired glucose-tolerant state, whereas type 2 diabetes is associated with a failure to secrete adequate amounts of GIP.

    Elevated plasma glucose-dependent insulinotropic polypeptide associates with hyperinsulinemia in impaired glucose tolerance.
    Theodorakis MJ, Carlson O, Muller DC, Egan JM.

    01/21/2010
    activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway

    Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.
    Ehses JA, Pelech SL, Pederson RA, McIntosh CH.

    01/21/2010
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