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    ZFAS1 ZNFX1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 441951, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Taken together, our data identified that zinc finger antisense 1 might act as a valuable prognostic biomarker and potential therapeutic target for glioma

    Upregulation of long noncoding RNA zinc finger antisense 1 enhances epithelial-mesenchymal transition in vitro and predicts poor prognosis in glioma.
    Lv QL, Chen SH, Zhang X, Sun B, Hu L, Qu Q, Huang YT, Wang GH, Liu YL, Zhang YY, Zhou HH.

    04/8/2017
    The expression of ZFAS1 is positively correlated with TNM stage and appears to be a new prognostic factor in colorectal cancer. ZFAS1 promptes cell migration, invasive and metastasis ability of colorectal cancer cells.

    Upregulation of long noncoding RNA ZFAS1 predicts poor prognosis and prompts invasion and metastasis in colorectal cancer.
    Wang W, Xing C.

    03/25/2017
    ZFAS1 could exhibit a tumor oncogenic role in glioma progression.

    Long non-coding RNA ZFAS1 is an unfavourable prognostic factor and promotes glioma cell progression by activation of the Notch signaling pathway.
    Gao K, Ji Z, She K, Yang Q, Shao L.

    02/25/2017
    ata suggest that long non-coding RNA ZFAS1 may function as oncogene via destabilization of tumor suppressor protein p53 (p53) and through cyclin-dependent kinase 1 (CDK1)/cyclin B1 complex leading to cell cycle progression and inhibition of apoptosis.

    Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer.
    Thorenoor N, Faltejskova-Vychytilova P, Hombach S, Mlcochova J, Kretz M, Svoboda M, Slaby O., Free PMC Article

    11/12/2016
    Up-regulation of ZFAS1 is correlated with poor prognosis and metastasis in hepatocellular carcinoma patients.

    Amplification of Long Noncoding RNA ZFAS1 Promotes Metastasis in Hepatocellular Carcinoma.
    Li T, Xie J, Shen C, Cheng D, Shi Y, Wu Z, Deng X, Chen H, Shen B, Peng C, Li H, Zhan Q, Zhu Z.

    10/31/2015
    ZFAS1 is highly expressed in the mammary gland and is down-regulated in breast tumors compared to normal tissue

    SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer.
    Askarian-Amiri ME, Crawford J, French JD, Smart CE, Smith MA, Clark MB, Ru K, Mercer TR, Thompson ER, Lakhani SR, Vargas AC, Campbell IG, Brown MA, Dinger ME, Mattick JS., Free PMC Article

    07/11/2011
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