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    POLD1 DNA polymerase delta 1, catalytic subunit [ Homo sapiens (human) ]

    Gene ID: 5424, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

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    GeneRIFPubMed TitleDate
    Abasic sites can also affect the strand displacement activity of the lagging strand DNA pol delta that can be overcome through a polymerase switch, involving the combined physical and functional interaction of DNA pol beta and Flap endonuclease 1.

    The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.
    Maga G, van Loon B, Crespan E, Villani G, Hübscher U., Free PMC Article

    		01/21/2010
    Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)

    Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.
    Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Méjean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S.

    		03/25/2009
    Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)See all PubMed (2) articles

    Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.
    Monsees GM, Kraft P, Chanock SJ, Hunter DJ, Han J.

    Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
    Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, Hoang KN, Liu-Mares W, Hu JJ.

    		09/10/2008
    Observational study and meta-analysis of gene-disease association. (HuGE Navigator)

    Comprehensive analysis of DNA repair gene variants and risk of meningioma.
    Bethke L, Murray A, Webb E, Schoemaker M, Muir K, McKinney P, Hepworth S, Dimitropoulou P, Lophatananon A, Feychting M, Lönn S, Ahlbom A, Malmer B, Henriksson R, Auvinen A, Kiuru A, Salminen T, Johansen C, Christensen HC, Kosteljanetz M, Swerdlow A, Houlston R.

    		04/3/2008
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (8) articles

    Polymorphisms in the base excision repair pathway and graft-versus-host disease.
    Arora M, Lindgren B, Basu S, Nagaraj S, Gross M, Weisdorf D, Thyagarajan B.

    Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations.
    Thyagarajan B, Lindgren B, Basu S, Nagaraj S, Gross MD, Weisdorf DJ, Arora M.

    Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
    Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium.

    Genetic susceptibility to distinct bladder cancer subphenotypes.
    Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, EPICURO/Spanish Bladder Cancer Study investigators.

    PTEN identified as important risk factor of chronic obstructive pulmonary disease.
    Hosgood HD 3rd, Menashe I, He X, Chanock S, Lan Q.

    Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
    Hosgood HD 3rd, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q.

    Genetic variation in the base excision repair pathway and bladder cancer risk.
    Figueroa JD, Malats N, Real FX, Silverman D, Kogevinas M, Chanock S, Welch R, Dosemeci M, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Rothman N, García-Closas M.

    Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes.
    Sigurdson AJ, Hauptmann M, Chatterjee N, Alexander BH, Doody MM, Rutter JL, Struewing JP.

    		03/13/2008
    POLD1 gene mutations are not responsible for the elevated HPRT mutation rates in a colon cancer cell line

    Effect of exogenous MSH6 and POLD1 expression on the mutation rate of the HPRT locus in a human colon cancer cell line with mutator phenotype, DLD-1.
    Yabuta T, Shinmura K, Yamane A, Yamaguchi S, Takenoshita S, Yokota J.

    		01/21/2010
    ubiquitin and ubiquitin-like proteins modify the p66 and p12 subunits of DNA polymerase delta

    The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins.
    Liu G, Warbrick E.

    		01/21/2010
    Repair of clustered DNA lesions

    Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine.
    Budworth H, Dianova II, Podust VN, Dianov GL.

    		01/21/2010
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