| EphA4 is physically associated with alpha(IIb)beta(3) in resting platelets, increases its surface expression when platelets are activated, and colocalizes with alpha(IIb)beta(3) at sites of contact between platelets. | Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.
Prévost N, Woulfe DS, Jiang H, Stalker TJ, Marchese P, Ruggeri ZM, Brass LF., Free PMC Article | 01/21/2010 |
| Overexpression of EphA4 receptor is associated with pancreatic ductal adenocarcinoma | EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
Iiizumi M, Hosokawa M, Takehara A, Chung S, Nakamura T, Katagiri T, Eguchi H, Ohigashi H, Ishikawa O, Nakamura Y, Nakagawa H. | 01/21/2010 |
| The expression of EphA4 in astrocyte progenitor cells and in the astrocyte meshwork at the optic nerve head has implications for optic nerve pathologies. | Temporal regulation of EphA4 in astroglia during murine retinal and optic nerve development.
Petros TJ, Williams SE, Mason CA. | 01/21/2010 |
| FGF-receptor-mediated mitogen-activated protein kinase stimulation is potentiated in cells costimulated with ephrin-A1 | Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.
Yokote H, Fujita K, Jing X, Sawada T, Liang S, Yao L, Yan X, Zhang Y, Schlessinger J, Sakaguchi K., Free PMC Article | 01/21/2010 |