| Conformational dynamics of A30G alpha-synuclein that causes familial Parkinson disease. | Conformational dynamics of A30G α-synuclein that causes familial Parkinson disease.
Das D, Mattaparthi VSK. | 01/31/2024 |
| Neuronally Derived Extracellular Vesicle alpha-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease. | Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease.
Yan S, Jiang C, Janzen A, Barber TR, Seger A, Sommerauer M, Davis JJ, Marek K, Hu MT, Oertel WH, Tofaris GK., Free PMC Article | 01/11/2024 |
| Gut mucosal cells transfer alpha-synuclein to the vagus nerve. | Gut mucosal cells transfer α-synuclein to the vagus nerve.
Chandra R, Sokratian A, Chavez KR, King S, Swain SM, Snyder JC, West AB, Liddle RA., Free PMC Article | 01/8/2024 |
| Selenium and selenoproteins role in Parkinson's disease: Is there a link between selenoproteins and accumulated alpha-synuclein? | Selenium and selenoproteins role in Parkinson's disease: Is there a link between selenoproteins and accumulated alpha-synuclein?
Salaramoli S, Joshaghani HR, Shoeibi A, Hashemy SI. | 12/21/2023 |
| MLKL deficiency alleviates neuroinflammation and motor deficits in the alpha-synuclein transgenic mouse model of Parkinson's disease. | MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease.
Geng L, Gao W, Saiyin H, Li Y, Zeng Y, Zhang Z, Li X, Liu Z, Gao Q, An P, Jiang N, Yu X, Chen X, Li S, Chen L, Lu B, Li A, Chen G, Shen Y, Zhang H, Tian M, Zhang Z, Li J., Free PMC Article | 12/5/2023 |
| The C-terminus of alpha-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1beta. | The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β.
Birol M, Muñoz IID, Rhoades E., Free PMC Article | 11/27/2023 |
| Evaluation of alpha-synuclein in CNS-originating extracellular vesicles for Parkinsonian disorders: A systematic review and meta-analysis. | Evaluation of α-synuclein in CNS-originating extracellular vesicles for Parkinsonian disorders: A systematic review and meta-analysis.
Taha HB, Ati SS., Free PMC Article | 11/20/2023 |
| The interplay between alpha-Synuclein and NLRP3 inflammasome in Parkinson's disease. | The interplay between α-Synuclein and NLRP3 inflammasome in Parkinson's disease.
Huang Q, Yang P, Liu Y, Ding J, Lu M, Hu G. | 11/18/2023 |
| Elevated ApoE, ApoJ and lipoprotein-bound alpha-synuclein levels in cerebrospinal fluid from Parkinson's disease patients - Validation in the BioFIND cohort. | Elevated ApoE, ApoJ and lipoprotein-bound α-synuclein levels in cerebrospinal fluid from Parkinson's disease patients - Validation in the BioFIND cohort.
Paslawski W, Svenningsson P. | 11/16/2023 |
| Decreased serum levels of alpha-synuclein in patients with schizophrenia and their unaffected siblings. | Decreased serum levels of α-synuclein in patients with schizophrenia and their unaffected siblings.
Göverti D, Büyüklüoğlu N, Nazik Yüksel R, Kaya H, Yücel Ç, Göka E. | 11/15/2023 |
| Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization. | Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization.
Lurette O, Martín-Jiménez R, Khan M, Sheta R, Jean S, Schofield M, Teixeira M, Rodriguez-Aller R, Perron I, Oueslati A, Hebert-Chatelain E., Free PMC Article | 11/14/2023 |
| alpha-Synuclein induces deficiency in clathrin-mediated endocytosis through inhibiting synaptojanin1 expression. | α-Synuclein induces deficiency in clathrin-mediated endocytosis through inhibiting synaptojanin1 expression.
Song DY, Yuan L, Cui N, Feng C, Meng L, Wang XH, Xiang M, Liu D, Wang C, Zhang Z, Li JY, Li W. | 11/2/2023 |
| Inhibition of abnormal C/EBPbeta/alpha-Syn signaling pathway through activation of Nrf2 ameliorates Parkinson's disease-like pathology. | Inhibition of abnormal C/EBPβ/α-Syn signaling pathway through activation of Nrf2 ameliorates Parkinson's disease-like pathology.
Lin Z, Huang L, Cao Q, Luo H, Yao W, Zhang JC., Free PMC Article | 11/1/2023 |
| Saturation mutagenesis of alpha-synuclein reveals monomer fold that modulates aggregation. | Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation.
Chlebowicz J, Russ W, Chen D, Vega A, Vernino S, White CL 3rd, Rizo J, Joachimiak LA, Diamond MI., Free PMC Article | 11/1/2023 |
| Who Ever Said It Would Be Easy? Reflecting on Two Clinical Trials Targeting alpha-Synuclein. | Who Ever Said It Would Be Easy? Reflecting on Two Clinical Trials Targeting α-Synuclein.
Jensen PH, Schlossmacher MG, Stefanis L. | 10/25/2023 |
| Changes in alpha-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease. | Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.
Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci A., Free PMC Article | 09/19/2023 |
| The Bidirectional Interplay of alpha-Synuclein with Lipids in the Central Nervous System and Its Implications for the Pathogenesis of Parkinson's Disease. | The Bidirectional Interplay of α-Synuclein with Lipids in the Central Nervous System and Its Implications for the Pathogenesis of Parkinson's Disease.
Battis K, Xiang W, Winkler J., Free PMC Article | 09/15/2023 |
| Beyond Strains: Molecular Diversity in Alpha-Synuclein at the Center of Disease Heterogeneity. | Beyond Strains: Molecular Diversity in Alpha-Synuclein at the Center of Disease Heterogeneity.
Wojewska MJ, Otero-Jimenez M, Guijarro-Nuez J, Alegre-Abarrategui J., Free PMC Article | 09/14/2023 |
| The Parkinson's disease-associated protein alpha-synuclein inhibits hepatoma by exosome delivery. | The Parkinson's disease-associated protein α-synuclein inhibits hepatoma by exosome delivery.
Hou TZ, Yang HM, Cheng YZ, Gu L, Zhang JN, Zhang H. | 09/12/2023 |
| Truncation or proteolysis of alpha-synuclein in Parkinsonism. | Truncation or proteolysis of α-synuclein in Parkinsonism.
Suthar SK, Lee SY. | 09/11/2023 |
| Advances in understanding the function of alpha-synuclein: implications for Parkinson's disease. | Advances in understanding the function of alpha-synuclein: implications for Parkinson's disease.
Calabresi P, Di Lazzaro G, Marino G, Campanelli F, Ghiglieri V., Free PMC Article | 09/7/2023 |
| Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent. | Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent.
Hou X, Chen TH, Koga S, Bredenberg JM, Faroqi AH, Delenclos M, Bu G, Wszolek ZK, Carr JA, Ross OA, McLean PJ, Murray ME, Dickson DW, Fiesel FC, Springer W., Free PMC Article | 08/31/2023 |
| Meta-analysis to Implement Alpha-Synuclein in Extracellular Vesicles as a Potential Biomarker for Parkinsons Disease. | Meta-analysis to Implement Alpha-Synuclein in Extracellular Vesicles as a Potential Biomarker for Parkinsons Disease.
Juárez-Vaquera VH, Rosetti-Sciutto MF, Morales-Ruiz V, Adalid-Peralta LV. | 08/30/2023 |
| Amyloids of alpha-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites. | Amyloids of α-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites.
Horvath I, Mohamed KA, Kumar R, Wittung-Stafshede P., Free PMC Article | 08/30/2023 |
| The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis. | The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis.
Sant'Anna R, Robbs BK, de Freitas JA, Dos Santos PP, König A, Outeiro TF, Foguel D., Free PMC Article | 08/25/2023 |