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    SHISAL2B shisa like 2B [ Homo sapiens (human) ]

    Gene ID: 100132916, updated on 28-Oct-2024

    Summary

    Official Symbol
    SHISAL2Bprovided by HGNC
    Official Full Name
    shisa like 2Bprovided by HGNC
    Primary source
    HGNC:HGNC:34236
    See related
    Ensembl:ENSG00000145642 MIM:620219; AllianceGenome:HGNC:34236
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM159B
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in stomach (RPKM 2.5), pancreas (RPKM 0.8) and 3 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See SHISAL2B in Genome Data Viewer
    Location:
    5q12.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (64690503..64718190)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (65510627..65538314)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (63986330..64014017)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900984 Neighboring gene NANOG hESC enhancer GRCh37_chr5:63984741-63985242 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:63986301-63986801 Neighboring gene mitochondrial ribosomal protein L49 pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:64001261-64002034 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:64002035-64002806 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:64010595-64011198 Neighboring gene SREK1 interacting protein 1 Neighboring gene uncharacterized LOC124900985 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16053 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:64063900-64065099 Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene MPRA-validated peak5266 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:64235623-64236166 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:64236167-64236709 Neighboring gene MPRA-validated peak5267 silencer

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein shisa-like-2B
    Names
    family with sequence similarity 159 member B
    membrane protein FAM159B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164442.2NP_001157914.1  protein shisa-like-2B

      See identical proteins and their annotated locations for NP_001157914.1

      Status: VALIDATED

      Source sequence(s)
      BQ271827, BU785751, BU952508
      Consensus CDS
      CCDS47220.1
      UniProtKB/Swiss-Prot
      A6NKW6
      Related
      ENSP00000373726.5, ENST00000389074.6
      Conserved Domains (1) summary
      pfam13908
      Location:889
      Shisa; Wnt and FGF inhibitory regulator

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      64690503..64718190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      65510627..65538314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)