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    PAGE1 PAGE family member 1 [ Homo sapiens (human) ]

    Gene ID: 8712, updated on 19-Sep-2024

    Summary

    Official Symbol
    PAGE1provided by HGNC
    Official Full Name
    PAGE family member 1provided by HGNC
    Primary source
    HGNC:HGNC:4107
    See related
    Ensembl:ENSG00000068985 MIM:300288; AllianceGenome:HGNC:4107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AL5; CT16.3; GAGE-9; GAGEB1; PAGE-1
    Summary
    This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the other gene family members, this gene does not encode an antigenic peptide. Nothing is presently known about the function of this protein. [provided by RefSeq, Jul 2008]
    Expression
    Restricted expression toward testis (RPKM 6.3) See more
    Orthologs
    NEW
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    Genomic context

    See PAGE1 in Genome Data Viewer
    Location:
    Xp11.23
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (49687447..49695984, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (49003279..49011889, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49452050..49460587, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene voltage dependent anion channel 1 pseudogene 2 Neighboring gene spalt like transcription factor 1 pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:49593810-49594310 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:49600770-49601270 Neighboring gene Sharpr-MPRA regulatory region 10598 Neighboring gene PAGE family member 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:49639467-49639967 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20846 Neighboring gene USP27X divergent transcript

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    P antigen family member 1
    Names
    G antigen 9
    G antigen family B member 1
    G antigen, family B, 1 (prostate associated)
    P antigen family, member 1 (prostate associated)
    prostate associated gene 1
    prostate-associated gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_012550.1 RefSeqGene

      Range
      5010..13547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_003785.4NP_003776.2  P antigen family member 1

      See identical proteins and their annotated locations for NP_003776.2

      Status: REVIEWED

      Source sequence(s)
      AC231643, BC004861, BU941413
      Consensus CDS
      CCDS14327.1
      UniProtKB/Swiss-Prot
      O75459, Q6FGM3, Q9BSS7
      Related
      ENSP00000365320.3, ENST00000376150.4
      Conserved Domains (1) summary
      pfam05831
      Location:198
      GAGE; GAGE protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      49687447..49695984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011543998.3XP_011542300.1  P antigen family member 1 isoform X1

      See identical proteins and their annotated locations for XP_011542300.1

      UniProtKB/Swiss-Prot
      O75459, Q6FGM3, Q9BSS7
      Conserved Domains (1) summary
      pfam05831
      Location:198
      GAGE; GAGE protein

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      49003279..49011889 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054328038.1XP_054184013.1  P antigen family member 1 isoform X1

      UniProtKB/Swiss-Prot
      O75459, Q6FGM3, Q9BSS7