Samd13 sterile alpha motif domain containing 13 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Samd13provided by RGD
Official Full Name: sterile alpha motif domain containing 13provided by RGD
Primary source: RGD:708544
See related: EnsemblRapid:ENSRNOG00000016432 AllianceGenome:RGD:708544
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Djl; rDJL
Summary: Predicted to enable protein folding chaperone; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone-mediated protein folding. Predicted to be active in cytoplasm and nucleus. Orthologous to human SAMD13 (sterile alpha motif domain containing 13). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Testes (RPKM 322.6) and Heart (RPKM 22.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 2q44

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (238194962..238200790, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (235534699..235540527, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (252500143..252537490, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

a novel DnaJ homologue, rDJL was identified in rat testis. (rDJL)
Title: Identification and characterization of rDJL, a novel member of the DnaJ protein family, in rat testis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables Hsp70 protein binding	IEA Inferred from Electronic Annotation more info
enables protein folding chaperone	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in chaperone-mediated protein folding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: sterile alpha motif domain-containing protein 13

Names: dnaj-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_020089.2 → NP_064474.1 sterile alpha motif domain-containing protein 13

See identical proteins and their annotated locations for NP_064474.1

Status: PROVISIONAL

Source sequence(s)

BC083558

UniProtKB/TrEMBL

A6HWE8, F7FMA6, Q9QZW8

Related

ENSRNOP00000021984.4, ENSRNOT00000021984.6

Conserved Domains (2) summary

COG0484
Location:2 → 67

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

pfam00226
Location:3 → 66

DnaJ; DnaJ domain