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    Gng7 G protein subunit gamma 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 58979, updated on 2-Nov-2024

    Summary

    Official Symbol
    Gng7provided by RGD
    Official Full Name
    G protein subunit gamma 7provided by RGD
    Primary source
    RGD:61860
    See related
    EnsemblRapid:ENSRNOG00000019857 AllianceGenome:RGD:61860
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hg3b
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of adenylate cyclase activity. Predicted to act upstream of or within behavioral fear response; locomotory behavior; and receptor guanylyl cyclase signaling pathway. Is active in Schaffer collateral - CA1 synapse; parallel fiber to Purkinje cell synapse; and synaptic vesicle membrane. Orthologous to human GNG7 (G protein subunit gamma 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 84.4) and Kidney (RPKM 12.3) See more
    Orthologs
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    Genomic context

    See Gng7 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9348148..9411924)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8697458..8761239)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11565740..11629519)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093772 Neighboring gene DIRAS family GTPase 1 Neighboring gene uncharacterized LOC102553301 Neighboring gene transfer RNA proline (anticodon AGG) 48 Neighboring gene growth arrest and DNA-damage-inducible, beta Neighboring gene uncharacterized LOC134479806 Neighboring gene lamin B2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding  
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse PubMed 
    part_of heterotrimeric G-protein complex  
    part_of heterotrimeric G-protein complex PubMed 
    is_active_in parallel fiber to Purkinje cell synapse PubMed 
    is_active_in synapse  
    is_active_in synaptic vesicle membrane PubMed 

    General protein information

    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
    Names
    guanine nucleotide binding protein (G protein), gamma 7 subunit
    guanine nucleotide binding protein, gamma 7
    heterotrimeric guanine nucleotide-binding protein 3b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024138.1NP_077052.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

      See identical proteins and their annotated locations for NP_077052.1

      Status: PROVISIONAL

      Source sequence(s)
      L23219
      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      9348148..9411924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017595070.3XP_017450559.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1

      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs
    2. XM_039079813.2XP_038935741.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1

      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Related
      ENSRNOP00000109030.1, ENSRNOT00000110558.2
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs
    3. XM_039079814.2XP_038935742.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1

      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs
    4. XM_039079815.2XP_038935743.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1

      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs
    5. XM_039079812.2XP_038935740.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1

      UniProtKB/Swiss-Prot
      P43425, Q45QK4
      Conserved Domains (1) summary
      smart00224
      Location:869
      GGL; G protein gamma subunit-like motifs
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