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    Rbpms RNA binding protein, mRNA processing factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498642, updated on 28-Oct-2024

    Summary

    Official Symbol
    Rbpmsprovided by RGD
    Official Full Name
    RNA binding protein, mRNA processing factorprovided by RGD
    Primary source
    RGD:1561067
    See related
    EnsemblRapid:ENSRNOG00000013328 AllianceGenome:RGD:1561067
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RBP-MS; RGD1561067
    Summary
    Enables identical protein binding activity; molecular adaptor activity; and pre-mRNA binding activity. Involved in protein-containing complex assembly and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasmic stress granule; cytosol; and nucleoplasm. Orthologous to human RBPMS (RNA binding protein, mRNA processing factor). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Heart (RPKM 84.8), Kidney (RPKM 71.5) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rbpms in Genome Data Viewer
    Location:
    16q12.2-q12.3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (64942159..65098504)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (58239370..58395424)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (61954569..62109998)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120097493 Neighboring gene general transcription factor IIE subunit 2 Neighboring gene small integral membrane protein 18 Neighboring gene uncharacterized LOC120097494 Neighboring gene glutathione-disulfide reductase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA CDS binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables pre-mRNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables pre-mRNA intronic binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA-binding protein with multiple splicing
    Names
    RNA binding protein gene with multiple splicing
    RNA binding protein with multiple splicing

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271244.1NP_001258173.1  RNA-binding protein with multiple splicing

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      F2Z3S5
      Related
      ENSRNOP00000017883.4, ENSRNOT00000017883.7
      Conserved Domains (1) summary
      cd12682
      Location:2398
      RRM_RBPMS; RNA recognition motif (RRM) found in vertebrate RNA-binding protein with multiple splicing (RBP-MS)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      64942159..65098504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253241.5XP_006253303.1  RNA-binding protein with multiple splicing isoform X3

      Conserved Domains (1) summary
      cd12682
      Location:2398
      RRM_RBPMS; RNA recognition motif in vertebrate RNA-binding protein with multiple splicing (RBP-MS)
    2. XM_006253238.5XP_006253300.1  RNA-binding protein with multiple splicing isoform X1

      Related
      ENSRNOP00000081138.1, ENSRNOT00000119714.2
      Conserved Domains (1) summary
      cd12682
      Location:2398
      RRM_RBPMS; RNA recognition motif in vertebrate RNA-binding protein with multiple splicing (RBP-MS)
    3. XM_006253240.5XP_006253302.1  RNA-binding protein with multiple splicing isoform X2

      UniProtKB/Swiss-Prot
      A0A8I5ZR01, A0A8I6G705, F1M9Y9
      UniProtKB/TrEMBL
      A0A8I6AAP9
      Related
      ENSRNOP00000111391.1, ENSRNOT00000144605.1
      Conserved Domains (1) summary
      cd12682
      Location:2398
      RRM_RBPMS; RNA recognition motif (RRM) found in vertebrate RNA-binding protein with multiple splicing (RBP-MS)
    4. XM_063275646.1XP_063131716.1  RNA-binding protein with multiple splicing isoform X2

      UniProtKB/Swiss-Prot
      A0A8I5ZR01, A0A8I6G705, F1M9Y9

    RNA

    1. XR_010058306.1 RNA Sequence

      Related
      ENSRNOT00000113205.2
    2. XR_010058307.1 RNA Sequence

    3. XR_010058308.1 RNA Sequence