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    Fdx2 ferredoxin 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313786, updated on 2-Nov-2024

    Summary

    Official Symbol
    Fdx2provided by RGD
    Official Full Name
    ferredoxin 2provided by RGD
    Primary source
    RGD:1561264
    See related
    EnsemblRapid:ENSRNOG00000023020 AllianceGenome:RGD:1561264
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fdx1l; RGD1561264
    Summary
    Predicted to enable electron transfer activity. Predicted to be involved in [2Fe-2S] cluster assembly and electron transport chain. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 123.1), Brain (RPKM 120.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fdx2 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27881091..27886230, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19604916..19609832, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (22086534..22091450, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 5 Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene ribonucleoprotein, PTB-binding 1 Neighboring gene tyrosine kinase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables electron transfer activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in P450-containing electron transport chain IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in [2Fe-2S] cluster assembly ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of [4Fe-4S] cluster assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in electron transport chain IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    ferredoxin-2, mitochondrial
    Names
    adrenodoxin-like protein, mitochondrial
    ferredoxin 1-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108002.1NP_001101472.1  ferredoxin-2, mitochondrial

      See identical proteins and their annotated locations for NP_001101472.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473993
      UniProtKB/TrEMBL
      A6JNN6, D4A8N2
      Related
      ENSRNOP00000028127.4, ENSRNOT00000028127.7
      Conserved Domains (1) summary
      PLN02593
      Location:59174
      PLN02593; adrenodoxin-like ferredoxin protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      27881091..27886230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010053956.1 RNA Sequence