Pigs phosphatidylinositol glycan anchor biosynthesis, class S [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pigsprovided by RGD
Official Full Name: phosphatidylinositol glycan anchor biosynthesis, class Sprovided by RGD
Primary source: RGD:1359436
See related: EnsemblRapid:ENSRNOG00000011366 AllianceGenome:RGD:1359436
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in attachment of GPI anchor to protein. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy. Orthologous to human PIGS (phosphatidylinositol glycan anchor biosynthesis class S). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 119.2), Lung (RPKM 97.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q25

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (63720568..63735255)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (63222611..63237190)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (65591638..65606175)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

D10Wox15 (e-PCR)
- UniSTS:118129

RH129323 (e-PCR)
- UniSTS:212630

D10Arb9 (e-PCR), detects polymorphism
- UniSTS:226265

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in attachment of GPI anchor to protein	IBA Inferred from Biological aspect of Ancestor more info
involved_in attachment of GPI anchor to protein	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of GPI-anchor transamidase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GPI-anchor transamidase complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: GPI transamidase component PIG-S

Names: phosphatidylinositol glycan, class S; phosphatidylinositol-glycan biosynthesis class S protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.